@prefix dce: <http://purl.org/dc/elements/1.1/>.
@prefix fma: <http://bioontology.org/projects/ontologies/fma/fmaOwlDlComponent_2_0#>.
@prefix owl: <http://www.w3.org/2002/07/owl#>.
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#>.
@prefix skos: <http://www.w3.org/2004/02/skos/core#>.
@prefix space: <http://eulersharp.sourceforge.net/2003/03swap/space#>.
@prefix physical: <http://eulersharp.sourceforge.net/2003/03swap/physicalResource#>.
@prefix human: <http://eulersharp.sourceforge.net/2003/03swap/human#>.
@prefix humanbody: <http://eulersharp.sourceforge.net/2003/03swap/humanBody#>.
@prefix boli: <http://www.agfa.com/w3c/2009/bodyLiquids#>.
@prefix clinskosch: <http://www.agfa.com/w3c/2009/clinicalSKOSSchemes#>.
@prefix humana: <http://www.agfa.com/w3c/2009/anatomy#>.

<http://www.agfa.com/w3c/2009/anatomy>
	a owl:Ontology;
	dce:title """Human Anatomy"""@en;
	dce:creator """Hans Cools, MD; Agfa Healthcare/Belgium"""@en;
	dce:contributor """Until 2010: Pieterjan De Potter; Ghent University - IBBT/ELIS - Multimedia Lab/Belgium"""@en;
	dce:publisher """Agfa Healthcare/Belgium"""@en;
	dce:description """Formal description of human anatomy with general and some more specific classes."""@en;
	skos:note """There is no intention to describe the whole of human anatomy. Therefore is relied currently on FMA and UniProt. The diversity of elements is due to their need in different projects."""@en;
	dce:source <http://sig.biostr.washington.edu/projects/fm/AboutFM.html>, <http://www.uniprot.org/uniprot/>;
	dce:format """OWL-Full"""@en;
	rdfs:comment """Copyright (c) 2009 Agfa-Gevaert Group / Ghent University - IBBT/ELIS - Multimedia Lab All Rights Reserved THIS IS UNPUBLISHED PROPRIETARY SOURCE CODE OF Agfa-Gevaert Group/ Ghent University - IBBT/ELIS - Multimedia Lab The copyright notice above does not evidence any actual or intended publication of such source code."""@en.

#
# CLASSES
#

humana:GenitourinarySystemStructure
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """genitourinary system structure"""@en;
	skos:definition """Any structure of the genitourinary system."""@en;
	rdfs:subClassOf humanbody:AnatomicalStructure;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clinskosch:sct20080731; skos:notation "21514008"^^clinskosch:sct20080731DT].

humana:UrinarySystemStructure
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """urinary system structure"""@en;
	skos:definition """Any structure of the urinary system."""@en;
	rdfs:subClassOf humana:GenitourinarySystemStructure;
	skos:exactMatch [
		a skos:Concept;
		skos:inScheme clinskosch:sct20080731;
		skos:notation "122489005"^^clinskosch:sct20080731DT
	].
	
humana:LowerUrinaryTractStructure
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """lower urinary tract structure"""@en;
	skos:definition """Any structure of the lower urinary tract."""@en;
	rdfs:subClassOf humana:UrinarySystemStructure;
	skos:exactMatch [
		a skos:Concept;
		skos:inScheme clinskosch:sct20080731;
		skos:notation "19787009"^^clinskosch:sct20080731DT
	].

humana:UpperUrinaryTractStructure
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """upper urinary tract structure"""@en;
	skos:definition """Any structure of the upper urinary tract."""@en;
	rdfs:subClassOf humana:UrinarySystemStructure;	
	skos:exactMatch [
		a skos:Concept;
		skos:inScheme clinskosch:sct20080731;
		skos:notation "431491007"^^clinskosch:sct20080731DT
	].

humana:UrethralStructure
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """urethral structure"""@en;
	rdfs:subClassOf humana:LowerUrinaryTractStructure;
	skos:exactMatch [
		a skos:Concept;
		skos:inScheme clinskosch:sct20080731;
		skos:notation "13648007"^^clinskosch:sct20080731DT
	].

humana:FemaleUrethralStructure
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """female urethral structure"""@en;
	owl:disjointWith humana:MaleUrethralStructure;
	rdfs:subClassOf humana:UrethralStructure, fma:Female_urethra;# , [
#		a owl:Restriction;
#		owl:onProperty humana:humanBodyStructureOf;
#		owl:allValuesFrom human:female
#	];
	skos:exactMatch [
		a skos:Concept; skos:inScheme clinskosch:sct20080731; skos:notation "25182001"^^clinskosch:sct20080731DT].

humana:FemaleExternalUrethralOrifice
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """female external urethral orifice"""@en;
	rdfs:subClassOf humana:FemaleUrethralStructure;
	owl:disjointWith humana:MaleExternalUrethralOrifice; 
	skos:exactMatch [
		a skos:Concept;
		skos:inScheme clinskosch:sct20080731;
		skos:notation "279479008"^^clinskosch:sct20080731DT
	].

humana:MaleUrethralStructure
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """male urethral structure"""@en;
	rdfs:subClassOf humana:UrethralStructure, fma:Male_urethra;
#	rdfs:subClassOf [
#		a owl:Restriction;
#		owl:onProperty humana:humanBodyStructureOf;
#		owl:allValuesFrom human:male
#	];
	skos:exactMatch [
		a skos:Concept;
		skos:inScheme clinskosch:sct20080731;
		skos:notation "82841003"^^clinskosch:sct20080731DT
	].

humana:MaleExternalUrethralOrifice
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """male external urethral orifice"""@en;
	rdfs:subClassOf humana:MaleUrethralStructure;
	skos:exactMatch [
		a skos:Concept;
		skos:inScheme clinskosch:sct20080731;
		skos:notation "279478000"^^clinskosch:sct20080731DT
	].
	
humana:NervousSystemStructure
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """nervous system structure"""@en;
	rdfs:subClassOf humanbody:AnatomicalStructure;
	skos:exactMatch [
		a skos:Concept;
		skos:inScheme clinskosch:sct20080731;
		skos:notation "25087005"^^clinskosch:sct20080731DT
	].
	
humana:CentralNervousSystemStructure
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """central nervous system structure"""@en;
	rdfs:subClassOf humana:NervousSystemStructure;
	skos:exactMatch [
		a skos:Concept;
		skos:inScheme clinskosch:sct20080731;
		skos:notation "21483005"^^clinskosch:sct20080731DT
	].

humana:MeningesStructure
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """meninges structure"""@en;
	rdfs:subClassOf humana:CentralNervousSystemStructure;
	skos:exactMatch [
		a skos:Concept;
		skos:inScheme clinskosch:sct20080731;
		skos:notation "1231004"^^clinskosch:sct20080731DT
	].

humana:SpinalCordMeningesStructure
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """spinal cord meninges structure"""@en;
	rdfs:subClassOf humana:MeningesStructure;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clinskosch:sct20080731; skos:notation "75559006"^^clinskosch:sct20080731DT].

humana:LumbarSpinalCordMeningesStructure
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """lumbar spinal cord meninges structure"""@en;
	rdfs:subClassOf humana:SpinalCordMeningesStructure;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clinskosch:sct20080731; skos:notation "303948000"^^clinskosch:sct20080731DT].

humana:SubarachnoidSpace
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """subarachnoid space"""@en;
	skos:definition """Space between arachnoid and pia mater layers of the meninges of brain and spinal cord."""@en;
	rdfs:subClassOf fma:Subarachnoid_space, humana:MeningesStructure;
	rdfs:subClassOf [
		a owl:Restriction; owl:onProperty space:contains; owl:allValuesFrom boli:CerebrospinalFluid];
	skos:exactMatch [
		a skos:Concept; skos:inScheme clinskosch:sct20080731; skos:notation "35951006"^^clinskosch:sct20080731DT].
	
humana:LumbarSubarachnoidSpace
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """lumbar subarachnoid space"""@en;
	rdfs:subClassOf humana:LumbarSpinalCordMeningesStructure, humana:SubarachnoidSpace;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clinskosch:sct20080731; skos:notation "261124005"^^clinskosch:sct20080731DT].

humana:CardiovascularSystemStructure
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """cardiovascular system structure"""@en;
	rdfs:subClassOf humanbody:AnatomicalStructure;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clinskosch:sct20080731; skos:notation "113257007"^^clinskosch:sct20080731DT].

humana:CardiacStructure
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """cardiac structure"""@en;
	rdfs:subClassOf humana:CardiovascularSystemStructure;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clinskosch:sct20080731; skos:notation "80891009"^^clinskosch:sct20080731DT].

humana:CardiacVentricularStructure
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """cardiac ventricular structure"""@en;
	rdfs:subClassOf humana:CardiacStructure;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clinskosch:sct20080731; skos:notation "21814001"^^clinskosch:sct20080731DT].

humana:VenousStructure
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """venous structure"""@en;
	skos:definition """Any venous structure."""@en;
	rdfs:subClassOf humana:CardiovascularSystemStructure;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clinskosch:sct20080731; skos:notation "29092000"^^clinskosch:sct20080731DT].

humana:RectalLumenStructure
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """rectal lumen structure"""@en;
	skos:definition """Any part of the rectal lumen."""@en;
	rdfs:subClassOf humanbody:AnatomicalStructure, fma:Lumen_of_rectum;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clinskosch:sct20080731; skos:notation "37207007"^^clinskosch:sct20080731DT].

humana:RectalLumen
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """rectal lumen"""@en;
	skos:definition """Rectal lumen as a whole."""@en;
	rdfs:subClassOf humana:RectalLumenStructure;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clinskosch:sct20080731; skos:notation "259740004"^^clinskosch:sct20080731DT].

humana:ReproductiveSystemStructure
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """reproductive system structure"""@en;
	rdfs:subClassOf humanbody:AnatomicalStructure.

humana:FemaleReproductiveSystemStructure
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """female reproductive system structure"""@en;
	rdfs:subClassOf humana:ReproductiveSystemStructure;
	rdfs:subClassOf [
		a owl:Restriction; owl:onProperty space:containedBy; owl:someValuesFrom [
			a owl:Restriction; owl:onProperty physical:complexityOf; owl:someValuesFrom human:Female]].

humana:Uterus
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """uterus"""@en;
	rdfs:subClassOf humana:FemaleReproductiveSystemStructure, fma:Uterus;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clinskosch:sct20080731; skos:notation "181452004"^^clinskosch:sct20080731DT].

humana:VaginalCanalStructure
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """vaginal canal"""@en;
	skos:definition """Any part of the vaginal canal."""@en;
	rdfs:subClassOf humana:FemaleReproductiveSystemStructure, fma:Lumen_of_vagina;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clinskosch:sct20080731; skos:notation "48001003"^^clinskosch:sct20080731DT].

humana:VaginalCanal
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """vaginal canal"""@en;
	skos:definition """Vaginal canal as a whole."""@en;
	rdfs:subClassOf humana:VaginalCanalStructure;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clinskosch:sct20080731; skos:notation "253155007"^^clinskosch:sct20080731DT].

humana:OralCavityStructure
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """oral cavity structure"""@en;
	skos:definition """Any structure of the oral cavity."""@en;
	rdfs:subClassOf humanbody:AnatomicalStructure, fma:Oral_cavity;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clinskosch:sct20080731; skos:notation "74262004"^^clinskosch:sct20080731DT].

humana:OralCavity
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """oral cavity"""@en;
	skos:definition """Oral cavity as a whole."""@en;
	rdfs:subClassOf humana:OralCavityStructure;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clinskosch:sct20080731; skos:notation "181220002"^^clinskosch:sct20080731DT].

humana:RimaOrisStructure
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """rima oris structure"""@en;
	skos:definition """Any structure of the oral opening."""@en;
	rdfs:subClassOf humana:OralCavityStructure;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clinskosch:sct20080731; skos:notation "3382006"^^clinskosch:sct20080731DT].

humana:RimaOris
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """rima oris"""@en;
	skos:definition """Oral opening as a whole."""@en;
	rdfs:subClassOf humana:RimaOrisStructure;
	space:containedBy humana:OralCavity;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clinskosch:sct20080731; skos:notation "368713006"^^clinskosch:sct20080731DT].

humana:ToothStructure
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """tooth structure"""@en;
	skos:definition """Structure of a tooth."""@en;
	rdfs:subClassOf humanbody:AnatomicalStructure, fma:Tooth;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clinskosch:sct20080731; skos:notation "38199008"^^clinskosch:sct20080731DT].

humana:Tooth
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """tooth"""@en;
	skos:definition """Tooth as a whole."""@en;
	rdfs:subClassOf humana:ToothStructure;
	space:containedBy humana:OralCavity;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clinskosch:sct20080731; skos:notation "302214001"^^clinskosch:sct20080731DT].

humana:EyeStructure
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """eye structure"""@en;
	rdfs:subClassOf humanbody:AnatomicalStructure;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clinskosch:sct20080731; skos:notation "81745001"^^clinskosch:sct20080731DT].

humana:Eye
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """eye"""@en;
	skos:definition """Eye as a whole."""@en;
	rdfs:subClassOf humana:EyeStructure, fma:Eye;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clinskosch:sct20080731; skos:notation "244486005"^^clinskosch:sct20080731DT].

humana:EarStructure
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """ear structure"""@en;
	rdfs:subClassOf humanbody:AnatomicalStructure;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clinskosch:sct20080731; skos:notation "117590005"^^clinskosch:sct20080731DT].

humana:Ear
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """ear"""@en;
	skos:definition """Ear as a whole."""@en;
	rdfs:subClassOf humana:EarStructure, fma:Ear;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clinskosch:sct20080731; skos:notation "1910005"^^clinskosch:sct20080731DT].

humana:EardrumSkin
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """eardrum skin"""@en;
	skos:definition """Tympanic membrane outer layer."""@en;
	rdfs:subClassOf humanbody:AnatomicalStructure, fma:Cuticular_layer_of_tympanic_membrane;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clinskosch:sct20080731; skos:notation "244079007"^^clinskosch:sct20080731DT].

humana:DNA
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """human deoxyribonucleic acid """@en;
	skos:definition """Deoxyribonucleic acid of a human."""@en;
	rdfs:subClassOf humanbody:AnatomicalStructure, fma:Deoxyribonucleic_acid.

humana:BLymphocyte
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """B lymphocyte"""@en;
	skos:definition """Lymphocyte formed in bone marrow and constituting humoral immune response."""@en;
	rdfs:subClassOf fma:B_lymphocyte.

humana:IGHV
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """immunoglobulin heavy chain variable region gene"""@en;
	skos:definition """Chromosome 14 immunoglobulin heavy locus variable region gene coding for immunoglobulin heavy chains."""@en;
	rdfs:subClassOf humana:DNA.

humana:ZAP70
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """zeta-chain-associated protein kinase 70"""@en;
#	skos:definition """."""@en;
	dce:source """https://debugit.agfa.net/ipdemo/rdfcat?uri=http://www.uniprot.org/uniprot/P43403.rdf&target=N3."""@en;
	rdfs:subClassOf humanbody:AnatomicalStructure.

humana:CD38
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """cluster of differentiation 38"""@en;
	skos:definition """Multifunctional ectoenzyme catalyzing the synthesis and hydrolysis of cyclic ADP-ribose (cADPR)."""@en;
	rdfs:subClassOf humanbody:AnatomicalStructure. # humana:LeucocyteSurfaceProtein

humana:ThymidineKinase
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """thymidine kinase"""@en;
	skos:definition """Phosphotransferase acting in introducing deoxythymidine into DNA at synthesis in cell division."""@en;
	rdfs:subClassOf humanbody:AnatomicalStructure. # humana:Phosphotransferase

humana:B2Microglobulin
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/anatomy#>;
	rdfs:label """β2 microglobulin"""@en;
	skos:definition """Major histocompatibility complex (MHC) class I molecule."""@en;
	rdfs:subClassOf humanbody:AnatomicalStructure. # humana:CellSurfaceProtein

#
# PROPERTIES
#

#humana:humanBodyStructureOf
#	skos:definition """Specifying a body structure of a human."""@en;
#	a owl:ObjectProperty;
#	rdfs:domain humana:HumanBodyStructure; # <- human body substance <- human body <- human
#	rdfs:range human:Human. # fetus included