@prefix dce: <http://purl.org/dc/elements/1.1/>.
@prefix owl: <http://www.w3.org/2002/07/owl#>.
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#>.
@prefix skos: <http://www.w3.org/2004/02/skos/core#>.
@prefix event: <http://eulersharp.sourceforge.net/2003/03swap/event#>.
@prefix clisko: <http://www.agfa.com/w3c/2009/clinicalSKOSSchemes#>.
@prefix quant: <http://eulersharp.sourceforge.net/2003/03swap/quantities#>.
@prefix units: <http://eulersharp.sourceforge.net/2003/03swap/units#>.
@prefix human: <http://eulersharp.sourceforge.net/2003/03swap/human#>.
@prefix clinlabproc: <http://www.agfa.com/w3c/2009/clinicalLabProcedure#>.
@prefix refuex: <http://www.agfa.com/w3c/2009/renalFunctionExamination#>.
<http://www.agfa.com/w3c/2009/renalFunctionExamination>
a owl:Ontology;
dce:title """Renal Function Examination"""@en;
dce:creator """Hans Cools, MD, Agfa Healthcare/Belgium"""@en;
dce:publisher """Agfa Healthcare/Belgium"""@en;
dce:description """Formal general description of renal function examination."""@en;
dce:source <http://www.urology-textbook.com/kidney-glomerular-filtration-rate.html>;
dce:format """OWL Full"""@en;
rdfs:comment """Copyright (c) 2009 Agfa-Gevaert Group. All Rights Reserved. THIS IS UNPUBLISHED PROPRIETARY SOURCE CODE OF Agfa-Gevaert Group. The copyright notice above does not evidence any actual or intended publication of such source code."""@en.
refuex:CreatinineSerumConcentration
a rdfs:Class;
rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/renalFunctionExamination#>;
rdfs:label """creatinine serum concentration"""@en;
skos:definition """."""@en;
rdfs:subClassOf quant:MassConcentration.
refuex:CreatinineSerumConcentrationMeasurement
a rdfs:Class;
rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/renalFunctionExamination#>;
rdfs:label """creatinine serum concentration measurement"""@en;
skos:definition """."""@en;
rdfs:subClassOf clinlabproc:Examination, quant:MassConcentrationMeasurement, [
a owl:Restriction; owl:onProperty quant:measurementOf; owl:someValuesFrom refuex:CreatinineSerumConcentration], [
a owl:Restriction; owl:onProperty quant:hasUnit; owl:someValuesFrom [
a owl:Restriction; owl:onProperty quant:unitOf; owl:someValuesFrom quant:MassConcentrationMeasurement]];
skos:exactMatch [
a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "113075003"^^clisko:sct20080731DT].
refuex:CreatinineClearanceRate
a rdfs:Class;
rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/renalFunctionExamination#>;
rdfs:label """creatinine clearance rate"""@en;
skos:definition """Volume of blood plasma cleared of creatinine, i.e. passing through the surface of the kidneys' filters, per unit of time."""@en;
rdfs:comment """Estimation of glomerular filtration rate."""@en;
rdfs:subClassOf quant:VolumeFLowRate.
refuex:CreatinineClearanceRateMeasurement
a rdfs:Class;
rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/renalFunctionExamination#>;
rdfs:label """creatinine clearance rate measurement"""@en;
rdfs:comment """E.g. estimated with http://eulersharp.sourceforge.net/2003/03swap/cockroftGaultCalculation#;
using modified formula of Cockroft and Gault: Cl_crea = (140-age) x BW / F x S_crea;
Cl_crea: creatinine clearance rate estimation in ml/min;
age value in years;
BW: body weight value in kg;
F: gender factor, female: 85, male: 72;
S_crea: creatinine serum concentration measurement value in mg/dl."""@en;
rdfs:subClassOf clinlabproc:Examination, quant:VolumeFLowRateMeasurement, [
a owl:Restriction; owl:onProperty quant:measurementOf; owl:someValuesFrom refuex:CreatinineClearanceRate], [
a owl:Restriction; owl:onProperty quant:hasUnit; owl:someValuesFrom units:milliliterPerMinute], [
a owl:Restriction; owl:onProperty quant:hasFactor; owl:someValuesFrom refuex:GenderFactor].
refuex:GenderFactor
a rdfs:Class;
rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/renalFunctionExamination#>;
rdfs:label """creatinine clearance rate estimation gender factor"""@en;
skos:definition """Factor for a gender in modified formula of Cockroft and Gault to estimate a creatinine clearance rate."""@en;
rdfs:subClassOf quant:Factor;
owl:oneOf (85 72).
refuex:hasGenderFactor
a owl:DatatypeProperty;
rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/renalFunctionExamination#>;
skos:definition """Specifying creatinine clearance rate measurement gender factor of a person."""@en;
rdfs:domain human:Person;
rdfs:range refuex:GenderFactor.