@prefix dce: <http://purl.org/dc/elements/1.1/>.
@prefix owl: <http://www.w3.org/2002/07/owl#>.
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#>.
@prefix skos: <http://www.w3.org/2004/02/skos/core#>.
@prefix clisko: <http://www.agfa.com/w3c/2009/clinicalSKOSSchemes#>.
@prefix event: <http://eulersharp.sourceforge.net/2003/03swap/event#>.
@prefix malneo: <http://www.agfa.com/w3c/2009/malignantNeoplasm#>.
@prefix clineva: <http://www.agfa.com/w3c/2009/clinicalEvaluation#>.
@prefix hurifa: <http://www.agfa.com/w3c/2009/humanRiskFactors#>.
@prefix humdis: <http://www.agfa.com/w3c/2009/humanDisorder#>.
@prefix genomab: <http://eulersharp.sourceforge.net/2003/03swap/genomeAbnormality#>.
@prefix genab: <http://www.agfa.com/w3c/2009/geneAbnormalities#>.

<http://www.agfa.com/w3c/2009/geneAbnormalities#>
	a owl:Ontology;
	dce:title """Gene Abnormalities"""@en;
	dce:creator """Hans Cools, MD; Agfa Healthcare/Belgium"""@en;
	dce:publisher """Agfa Healthcare/Belgium"""@en;
	dce:description """Formal description of human gene abnormalities."""@en;
	dce:format """OWL Full"""@en;
	rdfs:comment """Copyright (c) 2009 Agfa-Gevaert Group All Rights Reserved. THIS IS UNPUBLISHED PROPRIETARY SOURCE CODE OF Agfa-Gevaert Group The copyright notice above does not evidence any actual or intended publication of such source code."""@en.

#
# CLASSES
#

# CHROMOSOME 14

genab:IGHVmutation
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/geneAbnormalities#>;
	rdfs:label """immunoglobulin heavy chain variable region gene mutation"""@en;
	skos:definition """Mutation of a human immunoglobulin heavy chain variable region gene."""@en;
	rdfs:subClassOf genomab:GeneAbnormality, hurifa:CytogeneticRiskFactor.
	# genomab:mutationOf humana:IGHV.