@prefix dce: . @prefix dct: . @prefix owl: . @prefix rdfs: . @prefix skos: . @prefix snomedct: . @prefix rela: . @prefix state: . @prefix subfor: . @prefix ana: . @prefix clisko: . @prefix drug: . @prefix dradfo: . a owl:Ontology; dce:title """Drug Administration Forms"""@en; dce:creator """Hans Cools, MD, Agfa Healthcare/Belgium"""@en; dce:contributor """Until 2010: Pieterjan De Potter, Ghent University - IBBT/ELIS - Multimedia Lab/Belgium"""@en; dce:publisher """Agfa Healthcare/Belgium"""@en; dce:description """Formal description of drug administration forms."""@en; skos:note """Definitions from http://www.fda.gov/Drugs/DevelopmentApprovalProcess/FormsSubmissionRequirements/ElectronicSubmissions/DataStandardsManualmonographs/ucm071666.htm, unless indicated otherwise."""@en; dce:format """OWL-Full"""@en; rdfs:comment """Copyright (c) 2009 Agfa-Gevaert Group and Ghent University - IBBT/ELIS - Multimedia Lab. All Rights Reserved. THIS IS UNPUBLISHED PROPRIETARY SOURCE CODE OF Agfa-Gevaert Group and Ghent University - IBBT/ELIS - Multimedia Lab The copyright notice above does not evidence any actual or intended publication of such source code."""@en. # # CLASSES # dradfo:Aerosol a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """aerosol"""@en; skos:definition """A product that is packaged under pressure and contains therapeutically active ingredients that are released upon activation of an appropriate valve system; it is intended for topical application to the skin as well as local application into the nose (nasal aerosols), mouth (lingual aerosols), or lungs (inhalation aerosols)."""@en; rdfs:subClassOf drug:AdministrationForm; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "52262001"^^clisko:sct20080731DT]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "aer"^^clisko:kmehrdrugpres1DT]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "246"^^clisko:fdadf008DT]. dradfo:AerosolFoam a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """aerosol foam"""@en; skos:definition """A dosage form containing one or more active ingredients, surfactants, aqueous or nonaqueous liquids, and the propellants; if the propellant is in the internal (discontinuous) phase (i.e., of the oil-in-water type), a stable foam is discharged, and if the propellant is in the external (continuous) phase (i.e., of the water-in-oil type), a spray or a quick-breaking foam is discharged."""@en; rdfs:subClassOf dradfo:Aerosol; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "30843009"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "aerfoam"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "800"^^clisko:fdadf008DT ]. dradfo:MeteredAerosol a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """metered aerosol"""@en; skos:definition """A pressurized dosage form consisting of metered dose valves which allow for the delivery of a uniform quantity of spray upon each activation."""@en; rdfs:subClassOf dradfo:Aerosol; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "420847003"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "aermet"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "339"^^clisko:fdadf008DT ]. dradfo:AerosolPowder a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """aerosol powder"""@en; skos:definition """A product that is packaged under pressure and contains therapeutically active ingredients, in the form of a powder, that are released upon activation of an appropriate valve system."""@en; rdfs:subClassOf dradfo:Aerosol; rdfs:subClassOf subfor:Powder; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421104008"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "aerpwd"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "801"^^clisko:fdadf008DT ]. dradfo:Spray a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """spray"""@en; skos:definition """A liquid minutely divided as by a jet of air or steam."""@en; rdfs:subClassOf drug:AdministrationForm; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421720008"^^clisko:sct20080731DT], [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "spray"^^clisko:kmehrdrugpres1DT], [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "272"^^clisko:fdadf008DT]. dradfo:AerosolSpray a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """aerosol spray"""@en; skos:definition """An aerosol product which utilizes a compressed gas as the propellant to provide the force necessary to expel the product as a wet spray; it is applicable to solutions of medicinal agents in aqueous solvents."""@en; rdfs:subClassOf dradfo:Aerosol; rdfs:subClassOf dradfo:Spray; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421606006"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "aerspray"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "247"^^clisko:fdadf008DT ]. dradfo:Solid a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """solid dose form"""@en; rdfs:subClassOf drug:AdministrationForm; rela:hasState state:Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421378002"^^clisko:sct20080731DT]. dradfo:ChewableBar a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """chewable bar"""@en; skos:definition """A solid dosage form usually in the form of a rectangle that is meant to be chewed."""@en; rdfs:subClassOf dradfo:Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "429885007"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "barchew"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "347"^^clisko:fdadf008DT ]. dradfo:Bead a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """bead"""@en; skos:definition """A solid dosage form in the shape of a small ball."""@en; rdfs:subClassOf dradfo:Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "bead"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "317"^^clisko:fdadf008DT ]. dradfo:Implant a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """implant"""@en; skos:definition """A material containing drug intended to be inserted securely of deeply in a living site for growth, slow release, or formation of an organic union."""@en; rdfs:subClassOf dradfo:Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385286003"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "imp"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "715"^^clisko:fdadf008DT ]. dradfo:Extended-releaseBeadImplant a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """extended-release bead implant"""@en; skos:definition """A small sterile solid mass consisting of a highly purified drug intended for implantation in the body which would allow at least a reduction in dosing frequency as compared to that drug presented as a conventional dosage form."""@en; rdfs:subClassOf dradfo:Implant; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421271006"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "beadimper"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "802"^^clisko:fdadf008DT ]. dradfo:Block a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """block"""@en; skos:definition """Solid dosage form, usually in the shape of a square or rectangle."""@en; rdfs:subClassOf dradfo:Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "block"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "803"^^clisko:fdadf008DT ]. dradfo:Capsule a rdfs:Class, drug:administrationFormUnit; rdfs:isDefinedBy ; rdfs:label """capsule"""@en; skos:definition """A solid oral dosage form consisting of a shell and a filling. The shell is composed of a single sealed enclosure, or two halves that fit together and which are sometimes sealed with a band. Capsule shells may be made from gelatin, starch, or cellulose, or other suitable materials, may be soft or hard, and are filled with solid or liquid ingredients that can be poured or squeezed."""@en; rdfs:subClassOf drug:AdministrationForm; rdfs:subClassOf dradfo:Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385049006"^^clisko:sct20080731DT], [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "cap"^^clisko:kmehrdrugpres1DT], [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "600"^^clisko:fdadf008DT]. # dradfo:BySitePreparedFor # a rdfs:Class; # rdfs:isDefinedBy ; # rdfs:label """dosage form by site prepared for"""@en; # rdfs:subClassOf drug:AdministrationForm; # skos:exactMatch [ # a skos:Concept; # skos:inScheme clisko:sct20080731; # skos:notation "424387007"^^clisko:sct20080731DT]. #dradfo:OralCapsule # a rdfs:Class; # rdfs:isDefinedBy ; # rdfs:label """oral capsule"""@en; # rdfs:subClassOf dradfo:Capsule; # rdfs:subClassOf dradfo:Oral; # skos:exactMatch [ # a skos:Concept; # skos:inScheme clisko:sct20080731; # skos:notation "420692007"^^clisko:sct20080731DT # ]. dradfo:CoatedCapsule a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """coated capsule"""@en; skos:definition """A solid dosage form in which the drug is enclosed within either a hard or soft soluble container or 'shell' made from a suitable form of gelatin; additionally, the capsule is covered in a designated coating."""@en; #rdfs:subClassOf dradfo:OralCapsule; -> from snomedct skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385049006"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "capcoated"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "602"^^clisko:fdadf008DT ]. dradfo:Extended-releaseCoatedCapsule a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """extended-release coated capsule"""@en; skos:definition """A solid dosage form in which the drug is enclosed within either a hard or soft soluble container or 'shell' made from a suitable form of gelatin; additionally, the capsule is covered in a designated coating, and which releases a drug (or drugs) in such a manner to allow at least a reduction in dosing frequency as compared to that drug (or drugs) presented as a conventional dosage form."""@en; # rdfs:subClassOf dradfo:OralCapsule; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421338009"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "capcoateder"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "611"^^clisko:fdadf008DT ]. dradfo:CoatedPelletsCapsule a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """coated pellets capsule"""@en; skos:definition """A solid dosage form in which the drug is enclosed within either a hard or soft soluble container or 'shell' made from a suitable form of gelatin; the drug itself is in the form of granules to which varying amounts of coating have been applied."""@en; rdfs:subClassOf dradfo:CoatedCapsule; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "420293008"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "capcoatedpellets"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "603"^^clisko:fdadf008DT ]. dradfo:Delayed-releaseCapsule a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """delayed-release capsule"""@en; skos:definition """A solid dosage form in which the drug is enclosed within either a hard or soft soluble container made from a suitable form of gelatin, and which releases a drug (or drugs) at a time other than promptly after administration. Enteric-coated articles are delayed release dosage forms."""@en; # rdfs:subClassOf dradfo:OralCapsule; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421027002"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "capdr"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "620"^^clisko:fdadf008DT ]. dradfo:Delayed-releasePelletsCapsule a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """delayed-release pellets capsule"""@en; skos:definition """A solid dosage form in which the drug is enclosed within either a hard or soft soluble container or 'shell' made from a suitable form of gelatin; the drug itself is in the form of granules to which enteric coating has been applied, thus delaying release of the drug until its passage into the intestines."""@en; rdfs:subClassOf dradfo:Delayed-releaseCapsule; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "420767002"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "capdrpellets"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "621"^^clisko:fdadf008DT ]. dradfo:Extended-releaseCapsule a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """extended-release capsule"""@en; skos:definition """A solid dosage form in which the drug is enclosed within either a hard or soft soluble container made from a suitable form of gelatin, and which releases a drug (or drugs) in such a manner to allow a reduction in dosing frequency as compared to that drug (or drugs) presented as a conventional dosage form."""@en; # rdfs:subClassOf dradfo:OralCapsule; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421618002"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "caper"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "610"^^clisko:fdadf008DT ]. dradfo:Extended-releaseFilmCoatedCapsule a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """extended-release film coated capsule"""@en; skos:definition """A solid dosage form in which the drug is enclosed within either a hard or soft soluble container or 'shell' made from a suitable form of gelatin; additionally, the capsule is covered in a designated film coating, and which releases a drug (or drugs) in such a manner to allow at least a reduction in dosing frequency as compared to that drug (or drugs) presented as a conventional dosage form."""@en; rdfs:subClassOf dradfo:Extended-releaseCapsule; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421618002"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "capfilmcoateder"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "612"^^clisko:fdadf008DT ]. dradfo:CoatedGelatinCapsule a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """coated gelatin capsule"""@en; skos:definition """A solid dosage form in which the drug is enclosed within either a hard or soft soluble container made from a suitable form of gelatin; through a banding process, the capsule is coated with additional layers of gelatin so as to form a complete seal."""@en; rdfs:subClassOf dradfo:CoatedCapsule; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "capgelatincoated"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "605"^^clisko:fdadf008DT ]. dradfo:LiquidFilledCapsule a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """liquid filled capsule"""@en; skos:definition """A solid dosage form in which the drug is enclosed within a soluble, gelatin shell which is plasticized by the addition of a polyol, such as sorbitol or glycerin, and is therefore of a somewhat thicker consistency than that of a hard shell capsule; typically, the active ingredients are dissolved or suspended in a liquid vehicle."""@en; rdfs:subClassOf dradfo:Capsule; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "capliqfilled"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "606"^^clisko:fdadf008DT ]. dradfo:Device a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """device form"""@en; rdfs:subClassOf drug:AdministrationForm; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "423335001"^^clisko:sct20080731DT ]. dradfo:Cement a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """cement"""@en; skos:definition """A substance that serves to produce solid union between two surfaces."""@en; rdfs:subClassOf dradfo:Device; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "419202002"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "cement"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "252"^^clisko:fdadf008DT ]. dradfo:Inhaler a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """inhaler"""@en; rdfs:subClassOf drug:AdministrationForm; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "420317006"^^clisko:sct20080731DT ]. dradfo:BreathActivatedPowderInhaler a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """breath activated powder inhaler"""@en; rdfs:subClassOf dradfo:Inhaler; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "422197009"^^clisko:sct20080731DT ]. dradfo:Cigarette a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """cigarette"""@en; skos:definition """A narrow tube filled with material that is capable to burn with release of therapeutically-active substance(s) during the process of smoking."""@en; rdfs:subClassOf dradfo:BreathActivatedPowderInhaler; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "cigarette"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "253"^^clisko:fdadf008DT ]. dradfo:Cone a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """cone"""@en; skos:definition """A solid dosage form bounded by a circular base and the surface formed by line segments joining every point of the boundary of the base to a common vertex. A cone (usually containing antibiotics) is normally placed below the gingiva after a dental extraction."""@en; rdfs:subClassOf dradfo:Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421504000"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "cone"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "49"^^clisko:fdadf008DT ]. dradfo:Extended-release-core a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """extended-release-core"""@en; skos:definition """An ocular system placed in the eye from which the drug diffuses through a membrane at a constant rate over a specified period."""@en; rdfs:subClassOf drug:AdministrationForm; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "coreer"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "804"^^clisko:fdadf008DT ]. dradfo:Tablet a rdfs:Class, drug:administrationFormUnit; rdfs:isDefinedBy ; rdfs:label """tablet"""@en; skos:definition """Solid drug administration form with or without suitable diluents."""@en; rdfs:subClassOf drug:AdministrationForm, dradfo:Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385055001"^^clisko:sct20080731DT], [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "tab"^^clisko:kmehrdrugpres1DT], [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "500"^^clisko:fdadf008DT]. # dradfo:OralTablet # a rdfs:Class; # rdfs:isDefinedBy ; # rdfs:label """oral tablet"""@en; # rdfs:subClassOf dradfo:Tablet, dradfo:Oral; # skos:exactMatch [ # a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421026006"^^clisko:sct20080731DT]. dradfo:EffervescentTablet a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """effervescent tablet"""@en; skos:definition """A solid dosage form containing mixtures of acids (e.g., citric acid, tartaric acid) and sodium bicarbonate, which release carbon dioxide when dissolved in water; it is intended to be dissolved or dispersed in water before administration."""@en; #rdfs:subClassOf dradfo:OralTablet; -> from snomedct skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385058004"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "tabeffrv"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "503"^^clisko:fdadf008DT ]. dradfo:Liquid a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """liquid"""@en; skos:definition """A drug administration form consisting of a liquid substance."""@en; rdfs:subClassOf drug:AdministrationForm; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "420699003"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "liq"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "299"^^clisko:fdadf008DT ]. dradfo:Solution a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """solution"""@en; skos:definition """A drug administration form as homogeneous liquid mixture, containing one or more substances, wherein a solute is dissolved in a solvent."""@en; rdfs:subClassOf dradfo:Liquid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "77899000"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "sol"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "138"^^clisko:fdadf008DT ]. dradfo:InjectionSolution a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """injection solution"""@en; skos:definition """A liquid preparation containing one or more drug substances dissolved in a suitable solvent or mixture of mutually miscible solvents that is suitable for injection."""@en; rdfs:subClassOf dradfo:Solution, dradfo:Injection; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385219001"^^clisko:sct20080731DT], [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "injsol"^^clisko:kmehrdrugpres1DT], [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "708"^^clisko:fdadf008DT]. dradfo:Semi-Solid a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """semi-solid dose form"""@en; rdfs:subClassOf drug:AdministrationForm; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "420275007"^^clisko:sct20080731DT ]. dradfo:Cream a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """cream"""@en; skos:definition """An emulsion, semisolid dosage form, usually containing > 20% water and volatiles5 and/or < 50% hydrocarbons, waxes, or polyols as the vehicle. This dosage form is generally for external application to the skin or mucous membranes."""@en; rdfs:subClassOf dradfo:Semi-Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385099005"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "cream"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "805"^^clisko:fdadf008DT ]. dradfo:Crystal a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """crystal"""@en; skos:definition """A naturally produced angular solid of definite form in which the ultimate units from which it is built up are systematically arranged; they are usually evenly spaced on a regular space lattice."""@en; rdfs:subClassOf drug:AdministrationForm; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "crystal"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "51"^^clisko:fdadf008DT ]. #dradfo:Culture # a rdfs:Class; # rdfs:isDefinedBy ; # rdfs:label """culture"""@en; # skos:definition """the propagation of microorganisms or of living tissue cells in special media conducive to their growth."""@en; # rdfs:subClassOf drug:AdministrationForm; # skos:exactMatch [ # a skos:Concept; # skos:inScheme clisko:kmehrdrugpres1; # skos:notation "culture"^^clisko:kmehrdrugpres1DT # ]; # skos:exactMatch [ # a skos:Concept; # skos:inScheme clisko:fdadf008; # skos:notation "281"^^clisko:fdadf008DT # ]. dradfo:Diaphragm a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """diaphragm"""@en; skos:definition """A device usually dome-shaped, worn during copulation over the cervical mouth for prevention of conception or infection."""@en; rdfs:subClassOf drug:AdministrationForm; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "diaphragm"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "255"^^clisko:fdadf008DT ]. dradfo:Disc a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """disc"""@en; skos:definition """A circular plate-like organ or structure."""@en; #rdfs:subClassOf dradfo:UnitDose; -> from snomedct rdfs:subClassOf drug:AdministrationForm; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "427678004"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "disc"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "256"^^clisko:fdadf008DT ]. dradfo:Douche a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """douche"""@en; skos:definition """A liquid preparation, intended for the irrigative cleansing of the vagina, that is prepared from powders, liquid solutions, or liquid concentrates and contains one or more chemical substances dissolved in a suitable solvent or mutually miscible solvents."""@en; rdfs:subClassOf drug:AdministrationForm; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "douche"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "838"^^clisko:fdadf008DT ]. dradfo:Dressing a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """dressing"""@en; skos:definition """The application of various materials for protecting a wound."""@en; rdfs:subClassOf dradfo:Device; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "53288006"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "dressing"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "285"^^clisko:fdadf008DT ]. dradfo:Elexir a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """elixir"""@en; skos:definition """A clear, pleasantly flavored, sweetened hydroalcoholic liquid containing dissolved medicinal agents; it is intended for oral use."""@en; rdfs:subClassOf dradfo:Liquid; # rdfs:subClassOf dradfo:Oral; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385022006"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "elixir"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "807"^^clisko:fdadf008DT ]. dradfo:Emulsion a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """emulsion"""@en; skos:definition """A dosage form consisting of a two-phase system comprised of at least two immiscible liquids1, one of which is dispersed as droplets (internal or dispersed phase) within the other liquid (external or continuous phase), generally stabilized with one or more emulsifying agents. (Note: Emulsion is used as a dosage form term unless a more specific term is applicable, e.g. cream, lotion, ointment.)"""@en; rdfs:subClassOf dradfo:Liquid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "420386007"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "emulsion"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "52"^^clisko:fdadf008DT ]. dradfo:Enema a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """enema"""@en; skos:definition """A rectal preparation for therapeutic, diagnostic, or nutritive purposes."""@en; rdfs:subClassOf dradfo:Liquid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385186005"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "enema"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "286"^^clisko:fdadf008DT ]. dradfo:ComplementaryMedicine a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """complementary medicine dosage form"""@en; rdfs:subClassOf drug:AdministrationForm; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421563008"^^clisko:sct20080731DT ]. dradfo:Homoeopathic a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """homeopathic dose form"""@en; rdfs:subClassOf dradfo:ComplementaryMedicine; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "422255008"^^clisko:sct20080731DT ]. dradfo:Extract a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """extract"""@en; skos:definition """A concentrated preparation of vegetable or animal drugs obtained by removal of the active constituents of the respective drugs with a suitable menstrua, evaporation of all or nearly all of the solvent, and adjustment of the residual masses or powders to the prescribed standards."""@en; rdfs:subClassOf dradfo:Homoeopathic; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "422077001"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "extract"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "287"^^clisko:fdadf008DT ]. dradfo:Film a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """film"""@en; skos:definition """A thin layer or coating."""@en; rdfs:subClassOf dradfo:Semi-Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "420460001"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "film"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "61"^^clisko:fdadf008DT ]. dradfo:Extended-releaseFilm a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """extended-release film"""@en; skos:definition """A drug delivery system in the form of a film that releases the drug over an extended period in such a way as to maintain constant drug levels in the blood or target tissue."""@en; rdfs:subClassOf dradfo:Film; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421043009"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "filmer"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "810"^^clisko:fdadf008DT ]. dradfo:SolubleFilm a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """soluble film"""@en; skos:definition """A thin layer or coating which is susceptible to being dissolved when in contact with a liquid."""@en; rdfs:subClassOf dradfo:Film; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "filmsoluble"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "63"^^clisko:fdadf008DT ]. dradfo:Gaseous a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """gaseous"""@en; skos:definition """Any elastic aeriform fluid in which the molecules are separated from one another and so have free paths."""@en; rdfs:subClassOf drug:AdministrationForm; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421131006"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "gas"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "64"^^clisko:fdadf008DT ]. dradfo:Gel a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """gel"""@en; skos:definition """A semisolid dosage form that contains a gelling agent to provide stiffness to a solution or a colloidal dispersion. A gel may contain suspended particles."""@en; rdfs:subClassOf dradfo:Semi-Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385100002"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "gel"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "64"^^clisko:fdadf008DT ]. dradfo:Dental a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """dental dosage form"""@en; # rdfs:subClassOf dradfo:BySitePreparedFor; drug:hasAdministrationSite ana:Tooth; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385273007"^^clisko:sct20080731DT ]. dradfo:DentifriceGel a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """dentifrice gel"""@en; skos:definition """A combination of a dentifrice (formulation intended to clean and/or polish the teeth, and which may contain certain additional agents), and a gel. It is used with a toothbrush for the purpose of cleaning and polishing the teeth."""@en; rdfs:subClassOf dradfo:Gel; rdfs:subClassOf dradfo:Dental; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385088008"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "geldent"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "806"^^clisko:fdadf008DT ]. dradfo:Jelly a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """jelly"""@en; skos:definition """A class of gels, which are semisolid systems that consist of suspensions made up of either small inorganic particles or large organic molecules interpenetrated by a liquid--in which the structural coherent matrix contains a high portion of liquid, usually water."""@en; rdfs:subClassOf dradfo:Gel; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "geljelly"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "72"^^clisko:fdadf008DT ]. #dradfo:AerosolGenerator # a rdfs:Class; # rdfs:isDefinedBy ; # rdfs:label """aerosol generator"""@en; # skos:definition """An apparatus for the formation of vapor or gas from a liquid or solid by heat or chemical action. the term GENERATOR also applies to radioactive columns from which radionuclides are provided."""@en; # rdfs:subClassOf dradfo:Aerosol; # skos:exactMatch [ # a skos:Concept; # skos:inScheme clisko:sct20080731; # skos:notation "424179000"^^clisko:sct20080731DT # ]; # skos:exactMatch [ # a skos:Concept; # skos:inScheme clisko:kmehrdrugpres1; # skos:notation "generator"^^clisko:kmehrdrugpres1DT # ]; # skos:exactMatch [ # a skos:Concept; # skos:inScheme clisko:fdadf008; # skos:notation "289"^^clisko:fdadf008DT # ]. #not a dosage form dradfo:Globule a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """globule"""@en; skos:definition """Also called pellets or pilules, are made of pure sucrose, lactose, or other polysaccharides. They are formed into small globular masses of various sizes, and are medicated by placing them in a vial and adding the liquid drug attenuation in the proportion not less than one percent (v/w). After shaking, the medicated globules are dried at temperatures not to exceed 40 degrees Centigrade."""@en; rdfs:subClassOf dradfo:Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "globule"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "808"^^clisko:fdadf008DT ]. dradfo:Graft a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """graft"""@en; skos:definition """A slip of skin or of other tissue for implantation."""@en; rdfs:subClassOf drug:AdministrationForm; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "graft"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "290"^^clisko:fdadf008DT ]. dradfo:Granule a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """granule"""@en; skos:definition """A small particle or grain"""@en; rdfs:subClassOf dradfo:Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385043007"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "gran"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "78"^^clisko:fdadf008DT ]. # dradfo:OralGranule # a rdfs:Class; # rdfs:isDefinedBy ; # rdfs:label """oral granule"""@en; # rdfs:subClassOf dradfo:Granule, dradfo:Oral; # skos:exactMatch [ # a skos:Concept; # skos:inScheme clisko:sct20080731; # skos:notation "420509004"^^clisko:sct20080731DT]. dradfo:Delayed-releaseGranule a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """delayed-release granule"""@en; skos:definition """A small medicinal particle or grain to which an enteric or other coating has been applied, thus delaying release of the drug until its passage into the intestines."""@en; #rdfs:subClassOf dradfo:OralGranule; -> from snomedct skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "420757007"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "grandr"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "820"^^clisko:fdadf008DT ]. dradfo:EffervescentGranule a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """effervescent granule"""@en; skos:definition """A small particle or grain containing a medicinal agent in a dry mixture usually composed of sodium bicarbonate, citric acid, and tartaric acid which, when in contact with water, has the capability to release gas, resulting in effervescence."""@en; #rdfs:subClassOf dradfo:OralGranule; -> from snomedct skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385043007"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "graneffrv"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "80"^^clisko:fdadf008DT ]. dradfo:GranuleForSolution a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """granule for oral solution"""@en; skos:definition """A small medicinal particle or grain made available in its more stable dry form, to be reconstituted with solvent just before dispensing; the granules are so prepared to contain not only the medicinal agent, but the colorants, flavorants, and any other desired pharmaceutic ingredient."""@en; #rdfs:subClassOf dradfo:OralGranule; -> from snomedct skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385028005"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "granfsol"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "809"^^clisko:fdadf008DT ]. dradfo:GranuleForSuspension a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """granule for oral suspensions"""@en; skos:definition """A small medicinal particle or grain made available in its more stable dry form, to be reconstituted with solvent just before dispensing to form a suspension; the granules are so prepared to contain not only the medicinal agent, but the colorants, flavorants, and any other desired pharmaceutic ingredient."""@en; #rdfs:subClassOf dradfo:OralGranule; -> from snomedct skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385029002"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "granfsusp"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "819"^^clisko:fdadf008DT ]. dradfo:Extended-releaseGranuleForSuspension a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """extended-release granule for suspension"""@en; skos:definition """A small medicinal particle or grain made available in its more stable dry form, to be reconstituted with solvent just before dispensing to form a suspension; the extended release system achieves slow release of the drug over an extended period of time and maintains constant drug levels in the blood or target tissue."""@en; #rdfs:subClassOf dradfo:OralGranule; -> from snomedct skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421446006"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "granfsusper"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "811"^^clisko:fdadf008DT ]. dradfo:Gum a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """gum"""@en; skos:definition """A mucilaginous excretion from various plants."""@en; rdfs:subClassOf dradfo:Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "426210003"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "gum"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "84"^^clisko:fdadf008DT ]. dradfo:OralGum a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """oral gum"""@en; rdfs:subClassOf dradfo:Gum; #, dradfo:Oral; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385063000"^^clisko:sct20080731DT]. dradfo:Chewing-gum a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """chewing-gum"""@en; skos:definition """A sweetened and flavored insoluble plastic material of various shapes which when chewed, releases a drug substance into the oral cavity."""@en; # rdfs:subClassOf dradfo:OralGum; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385080001"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "gumchewing"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "85"^^clisko:fdadf008DT ]. dradfo:ResinGum a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """resin gum"""@en; skos:definition """Natural mixture of gum and resin, usually obtained as exudations from plants."""@en; rdfs:subClassOf dradfo:Gum; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "gumresin"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "87"^^clisko:fdadf008DT ]. dradfo:Inhalant a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """inhalant"""@en; skos:definition """A special class of inhalations consisting of a drug or combination of drugs, that by virtue of their high vapor pressure can be carried by an air current into the nasal passage where they exert their effect; the container from which the inhalant generally is administered is known as an inhaler."""@en; rdfs:subClassOf dradfo:Gaseous; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385217004"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "inhalant"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "293"^^clisko:fdadf008DT ]. dradfo:Parenteral a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """parenteral"""@en; # rdfs:subClassOf dradfo:BySitePreparedFor; #drug:hasAdministrationSite ana:? skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385287007"^^clisko:sct20080731DT ]. dradfo:Injection a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """injection"""@en; skos:definition """A sterile preparation intended for parenteral use; five distinct classes of injections exist as defined by the USP."""@en; rdfs:subClassOf dradfo:Parenteral; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385218009"^^clisko:sct20080731DT], [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "inj"^^clisko:kmehrdrugpres1DT], [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "700"^^clisko:fdadf008DT]. dradfo:InjectionEmulsion a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """injection emulsion"""@en; skos:definition """An emulsion consisting of a sterile, pyrogen-free preparation intended to be administered parenterally."""@en; rdfs:subClassOf dradfo:Parenteral; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385221006"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "injemulsion"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "701"^^clisko:fdadf008DT ]. dradfo:LipidComplexInjection a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """lipid complex injection"""@en; skos:definition """Injectable Lipid Complex Dosage Form."""@en; rdfs:subClassOf dradfo:Injection; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "injlipidcomplex"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "716"^^clisko:fdadf008DT ]. dradfo:PowderForReconstitutionForDrugProduct a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """powder for reconstitution for drug product"""@en; rdfs:subClassOf dradfo:Powder; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "420828001"^^clisko:sct20080731DT ]. dradfo:PowderForInjection a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """powder for injection"""@en; rdfs:subClassOf dradfo:Injection; rdfs:subClassOf dradfo:PowderForReconstitutionForDrugProduct; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385222004"^^clisko:sct20080731DT ]. dradfo:PowderForInjectionSolution a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """powder for injection solution"""@en; skos:definition """A sterile preparation intended for reconstitution to form a solution for parenteral use."""@en; # rdfs:subClassOf dradfo:InjectionPowder; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385223009"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "injpwdfsol"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "702"^^clisko:fdadf008DT ]. dradfo:PowderForInjectionSuspension a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """powder for injection suspension"""@en; skos:definition """A sterile preparation intended for reconstitution to form a suspension for parenteral use."""@en; # rdfs:subClassOf dradfo:InjectionPowder; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385224003"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "injpwdfsusp"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "703"^^clisko:fdadf008DT ]. dradfo:PowderForInjectableExtendedReleaseSuspension a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """powder for injectable extended release suspension"""@en; skos:definition """A dried preparation intended for reconstitution to form a suspension for parenteral use which has been formulated in a manner to allow at least a reduction in dosing frequency as compared to that drug presented as a conventional dosage form (e.g., as a solution)."""@en; rdfs:subClassOf dradfo:PowderForInjectionSuspension; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "422264003"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "injpwdfsusper"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "710"^^clisko:fdadf008DT ]. dradfo:LyophillisedPowderForInjectableLiposomalSuspension a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """lyophillised powder for injectable liposomal suspension"""@en; skos:definition """A sterile freeze dried preparation intended for reconstitution for parenteral use which has been formulated in a manner that would allow liposomes (a lipid bilayer vesicle usually composed of phospholipids which is used to encapsulate an active drug substance, either within a lipid bilayer or in an aqueous space) to be formed upon reconstitution."""@en; rdfs:subClassOf dradfo:PowderForInjectionSuspension; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "420656008"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "injpwdlyofls"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "713"^^clisko:fdadf008DT ]. dradfo:LyophillisedPowderForInjectableSolution a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """lyophillised powder for injectable solution"""@en; skos:definition """A dosage form intended for the solution prepared by lyophilization ('freeze drying'), a process which involves the removal of water from products in the frozen state at extremely low pressures; this is intended for subsequent addition of liquid to create a solution that conforms in all respects to the requirements for Injections."""@en; rdfs:subClassOf dradfo:PowderForInjectionSuspension; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421637006"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "injpwdlyofsol"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "705"^^clisko:fdadf008DT ]. dradfo:LyophillisedPowderForInjectableSuspension a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """lyophillised powder for injectable suspension"""@en; skos:definition """A liquid preparation, intended for parenteral use that contains solids suspended in a suitable fluid medium and conforms in all respects to the requirements for Sterile Suspensions; the medicinal agents intended for the suspension are prepared by lyophilization ('freeze drying'), a process which involves the removal of water from products in the frozen state at extremely low pressures."""@en; rdfs:subClassOf dradfo:PowderForInjectionSuspension; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421943006"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "injpwdlyofsusp"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "706"^^clisko:fdadf008DT ]. dradfo:LyophillisedPowderForInjectableExtendedReleaseSuspension a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """lyophillised powder for injectable extended release suspension"""@en; skos:definition """A sterile freeze dried preparation intended for reconstitution for parenteral use which has been formulated in a manner to allow at least a reduction in dosing frequency as compared to that drug presented as a conventional dosage form (e.g., as a solution)."""@en; rdfs:subClassOf dradfo:LyophillisedPowderForInjectableSuspension; rdfs:subClassOf dradfo:PowderForInjectableExtendedReleaseSuspension; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "injpwdlyofsusper"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "712"^^clisko:fdadf008DT ]. dradfo:InjectionConcentrate a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """injection concentrate"""@en; rdfs:subClassOf dradfo:Injection; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385227005"^^clisko:sct20080731DT ]. dradfo:ConcentrateForInjectableSolution a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """concentrate for injectable solution"""@en; skos:definition """A sterile preparation for parenteral use which, upon the addition of suitable solvents, yields a solution conforming in all respects to the requirements for Injections."""@en; rdfs:subClassOf dradfo:InjectionConcentrate; rdfs:subClassOf dradfo:InjectionSolution; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "injsolconc"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "709"^^clisko:fdadf008DT ]. dradfo:InjectionSuspension a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """injection suspension"""@en; skos:definition """A liquid preparation, suitable for injection, which consists of solid particles dispersed throughout a liquid phase in which the particles are not soluble. It can also consist of an oil phase dispersed throughout an aqueous phase, or vice-versa."""@en; rdfs:subClassOf dradfo:Parenteral; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385220007"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "injsusp"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "704"^^clisko:fdadf008DT ]. dradfo:Extended-releaseInjectableSuspension a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """extended-release injectable suspension"""@en; skos:definition """A sterile preparation intended for parenteral use which has been formulated in a manner to allow at least a reduction in dosing frequency as compared to that drug presented as a conventional dosage form (e.g., as a solution or a prompt drug-releasing, conventional solid dosage form)."""@en; rdfs:subClassOf dradfo:InjectionSuspension; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "420873008"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "injsusper"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "711"^^clisko:fdadf008DT ]. dradfo:LiposomalInjectableSuspension a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """liposomal injectable suspension"""@en; skos:definition """A liquid preparation, suitable for injection, which consists of an oil phase dispersed throughout an aqueous phase in such a manner that liposomes (a lipid bilayer vesicle usually composed of phospholipids which is used to encapsulate an active drug substance, either within a lipid bilayer or in an aqueous space) are formed."""@en; rdfs:subClassOf dradfo:InjectionSuspension; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421522002"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "injsusplipos"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "714"^^clisko:fdadf008DT ]. dradfo:SonicatedInjectableSuspension a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """sonicated injectable suspension"""@en; skos:definition """A liquid preparation, suitable for injection, which consists of solid particles dispersed throughout a liquid phase in which the particles are not soluble. In addition, the product is sonicated while a gas is bubbled through the suspension, and this results in the formation of microspheres by the solid particles."""@en; rdfs:subClassOf dradfo:InjectionSuspension; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421051007"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "injsuspson"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "840"^^clisko:fdadf008DT ]. dradfo:Insert a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """insert"""@en; skos:definition """A specially formulated and shaped non-encapsulated solid preparation intended to be placed into a non-rectal orifice of the body, where drug is released, generally for localized effects."""@en; rdfs:subClassOf dradfo:Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421532009"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "853"^^clisko:fdadf008DT ]. dradfo:Extended-releaseInsert a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """extended-release insert"""@en; skos:definition """A specially formulated and shaped non-encapsulated solid preparation intended to be placed into a non-rectal orifice of the body, where the medication is released, generally for localized effects; the extended release preparation is designed to allow for a reduction in dosing frequency."""@en; rdfs:subClassOf dradfo:Insert; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "420385006"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "inserter"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "812"^^clisko:fdadf008DT ]. dradfo:Irrigant a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """irrigant"""@en; skos:definition """A sterile solution intended to bathe or flush open wounds or body cavities; they're used topically, never parenterally."""@en; rdfs:subClassOf drug:AdministrationForm; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "irrigant"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "830"^^clisko:fdadf008DT ]. dradfo:IntrauterineDevice a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """intrauterine device"""@en; skos:definition """A device inserted and left in the uterus to prevent effective conception."""@en; # rdfs:subClassOf dradfo:BySitePreparedFor; rdfs:subClassOf drug:AdministrationForm; drug:hasAdministrationSite ana:Uterus; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385253002"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "iud"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "260"^^clisko:fdadf008DT ]. dradfo:Kit a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """kit"""@en; skos:definition """A packaged collection of related material."""@en; # rdfs:subClassOf dradfo:UnitDose; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "419179001"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "kit"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "261"^^clisko:fdadf008DT ]. dradfo:DentalLiner a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """dental liner"""@en; skos:definition """A material applied to the inside of the dental cavity, for protection or insulation of the surface."""@en; rdfs:subClassOf dradfo:Dental; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "linerdental"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "316"^^clisko:fdadf008DT ]. dradfo:Liniment a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """liniment"""@en; skos:definition """A solution or mixture of various substances in oil, alcoholic solutions of soap, or emulsions intended for external application."""@en; rdfs:subClassOf dradfo:Liquid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "63316001"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "liniment"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "298"^^clisko:fdadf008DT ]. dradfo:Stick a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """stick"""@en; skos:definition """A dosage form prepared in a relatively long and slender often cylindrical form."""@en; rdfs:subClassOf dradfo:Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "11190007"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "stick"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "273"^^clisko:fdadf008DT ]. dradfo:Lipstick a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """lipstick"""@en; skos:definition """A waxy solid, usually colored cosmetic, in stick form for the lips."""@en; # rdfs:subClassOf dradfo:DrugStick; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "lipstick"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "265"^^clisko:fdadf008DT ]. dradfo:Lotion a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """lotion"""@en; skos:definition """An emulsion, liquid dosage form. This dosage form is generally for external application to the skin."""@en; rdfs:subClassOf dradfo:Liquid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "17519006"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "lotion"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "300"^^clisko:fdadf008DT ]. dradfo:Lozenge a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """lozenge"""@en; skos:definition """A solid preparation containing one or more medicaments, usually in a flavored, sweetened base which is intended to dissolve or disintegrate slowly in the mouth. A lollipop is a lozenge on a stick."""@en; rdfs:subClassOf dradfo:Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385087003"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "lozenge"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "831"^^clisko:fdadf008DT ]. dradfo:Mouthwash #rdfs:subClassOf dradfo:Oromucosal_AND%2FORGingival; skos:definition """An aqueous solution which is most often used for its deodorant, refreshing, or antiseptic effect."""@en; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "70409003"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "mouthwash"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "832"^^clisko:fdadf008DT ]. dradfo:NotApplicable a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """not applicable"""@en; skos:definition """The use of a dosage form term is not relevant or appropriate."""@en; rdfs:subClassOf drug:AdministrationForm; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "notapplicable"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "313"^^clisko:fdadf008DT ]. dradfo:Oil a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """oil"""@en; skos:definition """An unctuous, combustible substance which is liquid, or easily liquefiable, on warming, and is soluble in ether but insoluble in water. Such substances, depending on their origin, are classified as animal, mineral, or vegetable oils."""@en; rdfs:subClassOf dradfo:Liquid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421890007"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "oil"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "98"^^clisko:fdadf008DT ]. dradfo:Ointment a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """ointment"""@en; skos:definition """A semisolid dosage form, usually containing <20% water and volatiles5 and >50% hydrocarbons, waxes, or polyols as the vehicle. This dosage form is generally for external application to the skin or mucous membranes."""@en; rdfs:subClassOf dradfo:Semi-Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385101003"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "ointment"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "101"^^clisko:fdadf008DT ]. dradfo:Packing a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """packing"""@en; skos:definition """A material, usually covered by or impregnated with a drug that is inserted into a body cavity or between the tooth enamel and the gingival margin."""@en; rdfs:subClassOf dradfo:Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "packing"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "839"^^clisko:fdadf008DT ]. dradfo:Paste a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """paste"""@en; skos:definition """A semisolid dosage form, containing a large proportion (20 – 50%) of solids finely dispersed in a fatty vehicle. This dosage form is generally for external application to the skin or mucous membranes."""@en; rdfs:subClassOf dradfo:Semi-Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "37937005"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "paste"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "103"^^clisko:fdadf008DT ]. dradfo:DentifricePaste a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """dentifrice paste"""@en; skos:definition """A paste formulation intended to clean and/or polish the teeth, and which may contain certain additional agents."""@en; rdfs:subClassOf dradfo:Paste; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421937009"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "pastedent"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "104"^^clisko:fdadf008DT ]. dradfo:Patch a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """drug patch"""@en; skos:definition """A drug delivery system that often contains an adhesive backing that is usually applied to an external site on the body. Its ingredients either passively diffuse from, or are actively transported from, some portion of the patch. Depending upon the patch, the ingredients are either delivered to the outer surface of the body or into the body. A patch is sometimes synonymous with the terms ‘extended release film’ and ‘system’."""@en; rdfs:subClassOf dradfo:Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "36875001"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "patch"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "843"^^clisko:fdadf008DT ]. dradfo:Extended-releasePatch a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """extended-release patch"""@en; skos:definition """A drug delivery system in the form of a patch that releases the drug in such a manner that a reduction in dosing frequency compared to that drug presented as a conventional dosage form (e.g., a solution or a prompt drug-releasing, conventional solid dosage form)."""@en; rdfs:subClassOf dradfo:Patch; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "patcher"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "813"^^clisko:fdadf008DT ]. dradfo:ElectricallyControlledExtended-releasePatch a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """electrically controlled extended-release patch"""@en; skos:definition """A drug delivery system in the form of a patch which is controlled by an electric current that releases the drug in such a manner that a reduction in dosing frequency compared to that drug presented as a conventional dosage form (e.g., a solution or a prompt drug-releasing, conventional solid dosage form)."""@en; rdfs:subClassOf dradfo:Extended-releasePatch; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "patcherelcon"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "814"^^clisko:fdadf008DT ]. dradfo:Pellet a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """pellet"""@en; skos:definition """A small sterile solid mass consisting of a highly purified drug (with or without excipients) made by the formation of granules, or by compression and molding."""@en; rdfs:subClassOf dradfo:Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "420768007"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "pellet"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "105"^^clisko:fdadf008DT ]. dradfo:ImplantablePellet a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """implantable pellet"""@en; skos:definition """A small sterile solid mass consisting of a highly purified drug (with or without excipients) made by the formation of granules, or by compression and molding; they are intended for implantation in the body (usually subcutaneously) for the purpose of providing continuous release of the drug over long periods of time."""@en; rdfs:subClassOf dradfo:Implant; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "420992009"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "pelletimp"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "844"^^clisko:fdadf008DT ]. dradfo:Extended-releaseCoatedPellets a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """extended-release coated pellets"""@en; skos:definition """A solid dosage form in which the drug itself is in the form of granules to which varying amounts of coating have been applied, and which releases a drug (or drugs) in such a manner to allow a reduction in dosing frequency as compared to that drug (or drugs) presented as a conventional dosage form."""@en; rdfs:subClassOf dradfo:Pellet; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421999009"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "pelletscoateder"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "842"^^clisko:fdadf008DT ]. dradfo:Pill a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """pill"""@en; skos:definition """A small, round solid dosage form containing a medicinal agent intended for oral administration."""@en; rdfs:subClassOf dradfo:Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "46992007"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "pill"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "107"^^clisko:fdadf008DT ]. dradfo:Plaster a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """plaster"""@en; skos:definition """Substance intended for external application made of such materials and of such consistency as to adhere to the skin and attach to a dressing; plasters are intended to afford protection and support and/or to furnish an occlusion and macerating action and to bring medication into close contact with the skin."""@en; rdfs:subClassOf dradfo:Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "36875001"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "plaster"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "108"^^clisko:fdadf008DT ]. dradfo:Poultice a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """poultice"""@en; skos:definition """A soft, moist mass of meal, herbs, seed, etc., usually applied hot in cloth that consists of gruel-like consistency."""@en; rdfs:subClassOf dradfo:Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385117009"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "poultice"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "109"^^clisko:fdadf008DT ]. #dradfo:Puff # owl:equivalentClass dradfo:Inhaler; # rdfs:subClassOf dradfo:UnitDose; # skos:exactMatch [ # a skos:Concept; # skos:inScheme clisko:sct20080731; # skos:notation "415215001"^^clisko:sct20080731DT # ]; # skos:exactMatch [ # a skos:Concept; # skos:inScheme clisko:kmehrdrugpres1; # skos:notation "puff"^^clisko:kmehrdrugpres1DT # ]. dradfo:Powder a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """powder"""@en; skos:definition """An intimate mixture of dry, finely divided drugs and/or chemicals that may be intended for internal or external use."""@en; rdfs:subClassOf subfor:Powder; rdfs:subClassOf dradfo:Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "85581007"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "pwd"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "110"^^clisko:fdadf008DT ]. dradfo:DentifricePowder a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """dentifrice powder"""@en; skos:definition """A powder formulation intended to clean and/or polish the teeth, and which may contain certain additional agents."""@en; rdfs:subClassOf dradfo:Powder; rdfs:subClassOf dradfo:Dental; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385091008"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "pwddent"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "115"^^clisko:fdadf008DT ]. dradfo:PowderForSolution a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """powder for solution"""@en; skos:definition """An intimate mixture of dry, finely divided drugs and/or chemicals, which, upon the addition of suitable vehicles, yields a solution."""@en; rdfs:subClassOf dradfo:PowderForReconstitutionForDrugProduct; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "420955009"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "pwdfsol"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "833"^^clisko:fdadf008DT ]. dradfo:PowderForSuspension a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """powder for suspension"""@en; skos:definition """An intimate mixture of dry, finely divided drugs and/or chemicals, which, upon the addition of suitable vehicles, yields a suspension (a liquid preparation containing the solid particles dispersed in the liquid vehicle)."""@en; rdfs:subClassOf dradfo:PowderForReconstitutionForDrugProduct; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421080003"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "pwdfsusp"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "834"^^clisko:fdadf008DT ]. dradfo:MeteredPowder a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """metered powder"""@en; skos:definition """A powder dosage form that is situated inside a container that has a mechanism to deliver a specified quantity."""@en; rdfs:subClassOf dradfo:Powder; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "420927005"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "pwdmet"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "841"^^clisko:fdadf008DT ]. dradfo:Rinse a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """rinse"""@en; skos:definition """A liquid used to cleanse by flushing."""@en; rdfs:subClassOf dradfo:Liquid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "rinse"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "303"^^clisko:fdadf008DT ]. dradfo:Salve a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """salve"""@en; skos:definition """A thick ointment or cerate (a fat or wax based preparation with a consistency between an ointment and a plaster)."""@en; rdfs:subClassOf dradfo:Semi-Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "salve"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "137"^^clisko:fdadf008DT ]. dradfo:Cutaneous # AND%2FORTransdermalDosageForm a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """cutaneous dosage form"""@en. #and/or transdermal: to be separated # rdfs:subClassOf dradfo:BySitePreparedFor; # drug:hasAdministrationSite ana:? # skos:exactMatch [ # a skos:Concept; # skos:inScheme clisko:sct20080731; # skos:notation "385275000"^^clisko:sct20080731DT # ]. dradfo:Shampoo a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """shampoo"""@en; skos:definition """A liquid soap or detergent used to clean the hair and scalp and is often used as a vehicle for dermatologic agents."""@en; rdfs:subClassOf dradfo:Semi-Solid; #rdfs:subClassOf dradfo:CutaneousAND%2FORTransdermalDosageForm; -> from snomedct skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385104006"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "shampoo"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "304"^^clisko:fdadf008DT ]. dradfo:ShampooSuspension a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """shampoo suspension"""@en; skos:definition """A liquid soap or detergent containing one or more solid, insoluble substances dispersed in a liquid vehicle that is used to clean the hair and scalp and is often used as a vehicle for dermatologic agents."""; rdfs:subClassOf dradfo:Shampoo; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "shampoosusp"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "193"^^clisko:fdadf008DT ]. dradfo:Soap a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """soap"""@en; skos:definition """Any compound of one or more fatty acids, or their equivalents, with an alkali; soap is detergent and is much employed in liniments, enemas, and in making pills. It is also a mild aperient, antacid and antiseptic."""@en; rdfs:subClassOf drug:AdministrationForm; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "soap"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "305"^^clisko:fdadf008DT ]. dradfo:SolutionConcentrate a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """solution concentrate"""@en; skos:definition """A liquid preparation (i.e., a substance that flows readily in its natural state) that contains a drug dissolved in a suitable solvent or mixture of mutually miscible solvents; the drug has been strengthened by the evaporation of its nonactive parts."""@en; rdfs:subClassOf dradfo:Solution; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "solconc"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "835"^^clisko:fdadf008DT ]. dradfo:SolutionForSlush a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """solution for slush"""@en; skos:definition """A solution for the preparation of an iced saline slush, which is administered by irrigation and used to induce regional hypothermia (in conditions such as certain open heart and kidney surgical procedures) by its direct application."""@en; rdfs:subClassOf dradfo:Solution; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "solfslush"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "321"^^clisko:fdadf008DT ]. dradfo:Extended-releaseGelFormingSolution a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """extended-release gel forming solution"""@en; skos:definition """A solution that forms a gel when it comes in contact with ocular fluid, and which allows at least a reduction in dosing frequency."""@en; rdfs:subClassOf dradfo:Solution; # rdfs:subClassOf dradfo:Ocular; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "solgfer"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "717"^^clisko:fdadf008DT ]. dradfo:Sponge a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """sponge"""@en; skos:definition """A porous, interlacing, absorbent material that contains a drug. It is typically used for applying or introducing medication, or for cleansing. A sponge usually retains its shape."""@en; rdfs:subClassOf dradfo:Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421288004"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "sponge"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "271"^^clisko:fdadf008DT ]. dradfo:MeteredSpray a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """metered spray"""@en; skos:definition """A non-pressurized dosage form consisting of valves which allow the dispensing of a specified quantity of spray upon each activation."""@en; rdfs:subClassOf dradfo:Spray; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421720008"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "spraymet"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "345"^^clisko:fdadf008DT ]. dradfo:Suspension a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """suspension"""@en; skos:definition """A liquid dosage form that contains solid particles dispersed in a liquid vehicle."""@en; rdfs:subClassOf dradfo:Liquid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "7946007"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "susp"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "177"^^clisko:fdadf008DT ]. dradfo:SpraySuspension a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """spray suspension"""@en; skos:definition """A liquid preparation containing solid particles dispersed in a liquid vehicle and in the form of coarse droplets or as finely divided solids to be applied locally, most usually to the nasal-pharyngeal tract, or topically to the skin."""@en; rdfs:subClassOf dradfo:Spray; rdfs:subClassOf dradfo:Suspension; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "spraysusp"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "195"^^clisko:fdadf008DT ]. dradfo:Strip a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """strip"""@en; skos:definition """A long narrow piece of material."""@en; rdfs:subClassOf dradfo:Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "strip"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "274"^^clisko:fdadf008DT ]. dradfo:Suppository a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """suppository"""@en; skos:definition """A solid body of various weights and shapes, adapted for introduction into the rectal orifice of the human body; they usually melt, soften, or dissolve at body temperature."""@en; rdfs:subClassOf dradfo:Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385194003"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "supp"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "173"^^clisko:fdadf008DT ]. dradfo:Extended-releaseSuppository a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """extended-release suppository"""@en; skos:definition """A drug delivery system in the form of a suppository that allows for a reduction in dosing frequency."""@en; rdfs:subClassOf dradfo:Suppository; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385194003"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "supper"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "815"^^clisko:fdadf008DT ]. #dradfo:OralSuspension # a rdfs:Class; # rdfs:isDefinedBy ; # rdfs:label """oral suspension"""@en; # rdfs:subClassOf dradfo:Suspension; # rdfs:subClassOf dradfo:Oral; # skos:exactMatch [ # a skos:Concept; # skos:inScheme clisko:sct20080731; # skos:notation "385024007"^^clisko:sct20080731DT # ]. dradfo:Extended-releaseSuspension a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """extended-release suspension"""@en; skos:definition """A liquid preparation consisting of solid particles dispersed throughout a liquid phase in which the particles are not soluble; the suspension has been formulated in a manner to allow at least a reduction in dosing frequency as compared to that drug presented as a conventional dosage form (e.g., as a solution or a prompt drug-releasing, conventional solid dosage form)."""@en; # rdfs:subClassOf dradfo:OralSuspension; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "422353003"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "susper"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "816"^^clisko:fdadf008DT ]. dradfo:Suture a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """suture"""@en; skos:definition """A strand or fiber used to hold wound edges in apposition during healing."""@en; rdfs:subClassOf drug:AdministrationForm; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "suture"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "275"^^clisko:fdadf008DT ]. dradfo:Swab a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """swab"""@en; skos:definition """A small piece of relatively flat absorbent material that contains a drug. A swab may also be attached to one end of a small stick. A swab is typically used for applying medication or for cleansing."""@en; rdfs:subClassOf dradfo:Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "swab"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "276"^^clisko:fdadf008DT ]. dradfo:Syrup a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """syrup"""@en; skos:definition """An oral solution containing high concentrations of sucrose or other sugars; the term has also been used to include any other liquid dosage form prepared in a sweet and viscid vehicle, including oral suspensions."""@en; rdfs:subClassOf dradfo:Liquid; # rdfs:subClassOf dradfo:Oral; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "syrup"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "307"^^clisko:fdadf008DT ]. dradfo:ChewableTablet a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """chewable tablet"""@en; skos:definition """A solid dosage form containing medicinal substances with or without suitable diluents that is intended to be chewed, producing a pleasant tasting residue in the oral cavity that is easily swallowed and does not leave a bitter or unpleasant after-taste."""@en; # rdfs:subClassOf dradfo:OralTablet; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "66076007"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "tabchew"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "501"^^clisko:fdadf008DT ]. dradfo:CoatedTablet a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """coated tablet"""@en; skos:definition """A solid dosage form that contains medicinal substances with or without suitable diluents and is covered with a designated coating."""@en; rdfs:subClassOf dradfo:Tablet; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "tabcoated"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "502"^^clisko:fdadf008DT ]. dradfo:Delayed-releaseTablet a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """delayed-release tablet"""@en; skos:definition """A solid dosage form which releases a drug (or drugs) at a time other than promptly after administration. Enteric-coated articles are delayed release dosage forms."""@en; # rdfs:subClassOf dradfo:OralTablet; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421374000"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "tabdr"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "520"^^clisko:fdadf008DT ]. dradfo:Delayed-releaseParticlesTablet a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """delayed-release particles tablet"""@en; skos:definition """A solid dosage form containing a conglomerate of medicinal particles that have been covered with a coating which releases a drug (or drugs) at a time other than promptly after administration. Enteric-coated articles are delayed release dosage forms."""@en; rdfs:subClassOf dradfo:Delayed-releaseTablet; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421535006"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "tabdrparticles"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "521"^^clisko:fdadf008DT ]. dradfo:Extended-releaseTablet a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """extended-release tablet"""@en; skos:definition """A solid dosage form containing a drug which allows at least a reduction in dosing frequency as compared to that drug presented in conventional dosage form."""@en; # rdfs:subClassOf dradfo:OralTablet; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "420627008"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "taber"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "510"^^clisko:fdadf008DT ]. dradfo:UltramicronisedTablet a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """ultramicronised tablet"""@en; # rdfs:subClassOf dradfo:OralTablet; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "420956005"^^clisko:sct20080731DT ]. dradfo:Film-CoatedTablet a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """film-coated tablet"""@en; skos:definition """A solid dosage form that contains medicinal substances with or without suitable diluents and is coated with a thin layer of a water-insoluble or water-soluble polymer."""@en; rdfs:subClassOf dradfo:UltramicronisedTablet; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385057009"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "tabfilmcoated"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "504"^^clisko:fdadf008DT ]. dradfo:Extended-releaseFilmCoatedTablet a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """extended-release film coated tablet"""@en; skos:definition """A solid dosage form that contains medicinal substances with or without suitable diluents and is coated with a thin layer of a water-insoluble or water-soluble polymer; the tablet is formulated in such manner as to make the contained medicament available over an extended period of time following ingestion."""@en; rdfs:subClassOf dradfo:Extended-releaseTablet; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "420378007"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "tabfilmcoateder"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "511"^^clisko:fdadf008DT ]. dradfo:MultilayerTablet a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """multilayer tablet"""@en; skos:definition """A solid dosage form containing medicinal substances that have been compressed to form a multiple-layered tablet or a tablet-within-a-tablet, the inner tablet being the core and the outer portion being the shell."""@en; rdfs:subClassOf dradfo:Tablet; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421932003"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "tabmultilayer"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "505"^^clisko:fdadf008DT ]. dradfo:Extended-releaseMultilayerTablet a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """extended-release multilayer tablet"""@en; skos:definition """A solid dosage form containing medicinal substances that have been compressed to form a multiple-layered tablet or a tablet-within-a-tablet, the inner tablet being the core and the outer portion being the shell, which, additionally, is covered in a designated coating; the tablet is formulated in such manner as to allow at least a reduction in dosing frequency as compared to that drug presented as a conventional dosage form."""@en; rdfs:subClassOf dradfo:MultilayerTablet; rdfs:subClassOf dradfo:Extended-releaseTablet; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "tabmultilayerer"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "512"^^clisko:fdadf008DT ]. dradfo:DispersibleTablet a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """dispersible tablet"""@en; # rdfs:subClassOf dradfo:OralTablet; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385036001"^^clisko:sct20080731DT ]. dradfo:OrallyDisintegratingTablet a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """orally disintegrating tablet"""@en; skos:definition """A solid dosage form containing medicinal substances which disintegrates rapidly, usually within a matter of seconds, when placed upon the tongue."""@en; # rdfs:subClassOf dradfo:OralTablet; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385036001"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "taborallydis"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "522"^^clisko:fdadf008DT ]. dradfo:SolubleTablet a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """soluble tablet"""@en; skos:definition """A solid dosage form that contains medicinal substances with or without suitable diluents and possesses the ability to dissolve in fluids."""@en; # rdfs:subClassOf dradfo:OralTablet; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385035002"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "tabsoluble"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "507"^^clisko:fdadf008DT ]. dradfo:SugarCoatedTablet a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """sugar coated tablet"""@en; skos:definition """A solid dosage form that contains medicinal substances with or without suitable diluents and is coated with a colored or an uncolored water-soluble sugar."""@en; rdfs:subClassOf dradfo:CoatedTablet; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "tabsugarcoated"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "508"^^clisko:fdadf008DT ]. dradfo:Tampon a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """tampon"""@en; skos:definition """A plug made of cotton, sponge, or oakum variously used in surgery to plug the nose, vagina, etc., for the control of hemorrhage or the absorption of secretions."""@en; rdfs:subClassOf dradfo:Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "420243009"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "tampon"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "277"^^clisko:fdadf008DT ]. dradfo:Tape a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """tape"""@en; skos:definition """A narrow woven fabric, or a narrow extruded synthetic (such as plastic), usually with an adhesive on one or both sides."""@en; rdfs:subClassOf dradfo:Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "tape"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "278"^^clisko:fdadf008DT ]. dradfo:Tincture a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """tincture"""@en; skos:definition """An alcoholic or hydroalcoholic solution prepared from vegetable materials or from chemical substances."""@en; rdfs:subClassOf dradfo:Liquid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "422186009"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "tincture"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "837"^^clisko:fdadf008DT ]. #dradfo:Pastille # a rdfs:Class; # rdfs:isDefinedBy ; # rdfs:label """pastille"""@en; # rdfs:subClassOf dradfo:Solid; # skos:exactMatch [ # a skos:Concept; # skos:inScheme clisko:sct20080731; # skos:notation "421079001"^^clisko:sct20080731DT # ]. dradfo:Troche a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """troche"""@en; skos:definition """A discoid-shaped solid containing the medicinal agent in a suitably flavored base; troches are placed in the mouth where they slowly dissolve, liberating the active ingredients."""@en; # rdfs:subClassOf dradfo:oral; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "421079001"^^clisko:sct20080731DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "troche"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "363"^^clisko:fdadf008DT ]. dradfo:Wafer a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """wafer"""@en; skos:definition """A thin slice of material containing a medicinal agent."""@en; rdfs:subClassOf dradfo:Solid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "wafer"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "245"^^clisko:fdadf008DT ]. dradfo:Ampule a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """ampule"""@en; skos:definition """A small glass vial that is sealed after filling and used chiefly as a container for a hypodermic injection solution."""@en; # http://www.thefreedictionary.com/ampule # rdfs:subClassOf dradfo:UnitDose; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "413516001"^^clisko:sct20080731DT ]. #dradfo:Ampoule owl:equivalentClass dradfo:Ampule. # synonyms outside ontology dradfo:Drops a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """drops"""@en; rdfs:subClassOf dradfo:Liquid; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "426684005"^^clisko:sct20080731DT ]. dradfo:Otic a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """otic"""@en; # rdfs:subClassOf dradfo:BySitePreparedFor; drug:hasAdministrationSite ana:Ear; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385277008"^^clisko:sct20080731DT ]. dradfo:EarDrops a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """ear drops"""@en; rdfs:subClassOf dradfo:Drops; rdfs:subClassOf dradfo:Otic; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385136004"^^clisko:sct20080731DT ]. dradfo:Ocular a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """ocular"""@en; # rdfs:subClassOf dradfo:BySitePreparedFor; drug:hasAdministrationSite ana:Eye; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385276004"^^clisko:sct20080731DT ]. dradfo:EyeDrops a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """eye drops"""@en; rdfs:subClassOf dradfo:Drops, dradfo:Ocular; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "385124005"^^clisko:sct20080731DT ]. dradfo:Unassigned a rdfs:Class; rdfs:isDefinedBy ; rdfs:label """unassigned"""@en; skos:definition """A dosage form has yet to be assigned."""@en; rdfs:subClassOf drug:AdministrationForm; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:kmehrdrugpres1; skos:notation "unassigned"^^clisko:kmehrdrugpres1DT ]; skos:exactMatch [ a skos:Concept; skos:inScheme clisko:fdadf008; skos:notation "900"^^clisko:fdadf008DT ]. # dradfo:BySitePreparedFor, dradfo:preparedForSite -> drug:hasAdministrationSite