@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#>.
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#>.
@prefix owl: <http://www.w3.org/2002/07/owl#>.
@prefix xsd: <http://www.w3.org/2001/XMLSchema#>.
@prefix dce: <http://purl.org/dc/elements/1.1/>.
@prefix quant: <http://eulersharp.sourceforge.net/2003/03swap/quantities#>.
@prefix event: <http://eulersharp.sourceforge.net/2003/03swap/event#>.
@prefix time: <http://eulersharp.sourceforge.net/2003/03swap/time#>.
@prefix agent: <http://eulersharp.sourceforge.net/2003/03swap/agent#>.
@prefix human: <http://eulersharp.sourceforge.net/2003/03swap/human#>.
@prefix heca: <http://www.agfa.com/w3c/2009/healthCare#>.
@prefix clineva: <http://www.agfa.com/w3c/2009/clinicalEvaluation#>.
@prefix humdis: <http://www.agfa.com/w3c/2009/humanDisorder#>.
@prefix ther: <http://www.agfa.com/w3c/2009/therapy#>.
@prefix drug: <http://www.agfa.com/w3c/2009/drugTherapy#>.
@prefix cll: <http://www.agfa.com/w3c/2009/chronicLymphocyticLeukemia#>.
@prefix chemo: <http://www.agfa.com/w3c/2009/chemotherapy#>.
@prefix imsup: <http://www.agfa.com/w3c/2009/immunosuppressants#>.
@prefix antineo: <http://www.agfa.com/w3c/2009/antineoplastics#>.
@prefix clintrial: <http://www.agfa.com/w3c/2009/clinicalTrial#>.
@prefix stemcelltrans: <http://www.agfa.com/w3c/2009/stemCellTransplantation#>.
@prefix cllwf: <http://www.agfa.com/w3c/2009/chronicLymphocyticLeukemiaWorkflow#>.
@prefix cllanalysis: <http://www.agfa.com/w3c/2009/chronicLymphocyticLeukemiaAnalysis#>.

<http://www.agfa.com/w3c/2009/chronicLymphocyticLeukemiaAnalysis>
	a owl:Ontology;
	dce:title """CLL Analysis"""@en;
	dce:creator """Hans Cools, MD; Agfa Healthcare, Belgium"""@en;
	dce:publisher """Agfa Healthcare, Belgium"""@en;
	dce:description """Formal description of analysis results of chronic lymphocytic leukemia as a set of class descriptions.
		A clinical question in a portal applicatioin GUI triggers one or more formal SPARQL queries.
		These queries retrieve the necessary formal data from a basic data set.
		This set triggers the execution of an N3 rule.
		This rule has in its premise the inferences and calculations to answer the clinical question when applied by a reasoner.
		The conclusion of the rule contains the formalism for answering the question by stating an instance of a class.
		The result of a rule is again queried with another SPARQL query and its result is shown in the portal."""@en;
	dce:format """OWL Full"""@en.


cllanalysis:CLLPatientDiagnosedInCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty clineva:gotDiagnosed; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty event:diagnosedDuring; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]]]]].

cllanalysis:CLLPatientInCertainPeriod
		a rdfs:class;
		rdfs:subClassOf human:Person, [
			a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
			a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
				rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
					a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
						time:begins [a xsd:dateTime];
						time:ends [a xsd:dateTime]]]]].

cllanalysis:ComorbidCLLPatientInCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue event:Event], [
				a owl:Restriction; owl:onProperty humdis:hasComorbidity; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue event:Event;
					a owl:Restriction; owl:onProperty time:endsAfterBeginningOf; owl:hasValue event:Event]]]].

cllanalysis:CLLPatientStagedBinetInCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]]], [
				a owl:Restriction; owl:onProperty event:hasStage; owl:hasValue [
					a cll:BinetStage;
					event:hasDateTime [a xsd:dateTime]]]]].

cllanalysis:CLLPatientStagedBinetAInCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, cllanalysis:CLLPatientStagedBinetInCertainPeriod, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
#				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
#					time:begins [a xsd:dateTime];
#					time:ends [a xsd:dateTime]]], [
				a owl:Restriction; owl:onProperty event:hasStage; owl:hasValue [
					a cll:BinetStageA;
					event:hasDateTime [a xsd:dateTime]]]]].

cllanalysis:CLLPatientStagedBinetBInCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, cllanalysis:CLLPatientStagedBinetInCertainPeriod, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
#				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
#					time:begins [a xsd:dateTime];
#					time:ends [a xsd:dateTime]]], [
				a owl:Restriction; owl:onProperty event:hasStage; owl:hasValue [
					a cll:BinetStageB;
					event:hasDateTime [a xsd:dateTime]]]]].

cllanalysis:CLLPatientStagedBinetCInCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, cllanalysis:CLLPatientStagedBinetInCertainPeriod, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
#				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
#					time:begins [a xsd:dateTime];
#					time:ends [a xsd:dateTime]]], [
				a owl:Restriction; owl:onProperty event:hasStage; owl:hasValue [
					a cll:BinetStageC;
					event:hasDateTime [a xsd:dateTime]]]]].

cllanalysis:CLLPatientFirstTreatedInCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]]], [
				a owl:Restriction; owl:onProperty ther:firstTreatedWith; owl:someValuesFrom ther:Therapy]]].

cllanalysis:CLLComorbidPatientFirstTreatedStandardlyInCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientFirstTreatedStandardlyInCertainPeriod, human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]]], [
				a owl:Restriction; owl:onProperty ther:firstTreatedWith; owl:someValuesFrom [
					rdfs:subClassOf cll:StandardComorbidTherapy]]]].

cllanalysis:CLLNonComorbidPatientFirstTreatedStandardlyInCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientFirstTreatedStandardlyInCertainPeriod, human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]]], [
				a owl:Restriction; owl:onProperty ther:firstTreatedWith; owl:someValuesFrom [
					rdfs:subClassOf cll:StandardNonComorbidTherapy]]]].

cllanalysis:CLLPatientFirstTreatedStandardlyInCertainPeriod

	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]]], [
				a owl:Restriction; owl:onProperty ther:firstTreatedWith; owl:someValuesFrom [
					rdfs:subClassOf cll:StandardTherapy]]]].

cllanalysis:CLLPatientFirstTreatedWithBendamustinInCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]]], [
				a owl:Restriction; owl:onProperty ther:firstTreatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Therapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientSecondarilyTreatedInCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]]], [
				a owl:Restriction; owl:onProperty ther:secondarilyTreatedWith; owl:someValuesFrom drug:Therapy]]].

cllanalysis:CLLPatientSecondarilyTreatedWithBendamustinInCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]]], [
				a owl:Restriction; owl:onProperty ther:secondarilyTreatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Therapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientTreatedWithAllogenicStemCellTransplantationInCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom stemcelltrans:AllogenicHematopoieticStemCellTransplantation]]].

cllanalysis:CLLPatientInTrialInCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]]]]], [
		a owl:Restriction; owl:onProperty clintrial:subjectIn; owl:someValuesFrom clintrial:Trial].

cllanalysis:CLLPatientTherapyPeriod1InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod1]]]]].

cllanalysis:CLLPatientTherapyPeriod2InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod2]]]]].

cllanalysis:CLLPatientTherapyPeriod3InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod3]]]]].

cllanalysis:CLLPatientTherapyPeriod4InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod4]]]]].

cllanalysis:CLLPatientTherapyPeriod5InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod5]]]]].

cllanalysis:CLLPatientTherapyPeriod6InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod6]]]]].

cllanalysis:CLLPatientTherapyPeriod7InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod7]]]]].

cllanalysis:CLLPatientTherapyPeriod8InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod8]]]]].

cllanalysis:CLLPatientTherapyPeriod9InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod9]]]]].

cllanalysis:CLLPatientTherapyPeriod10InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod10]]]]].

cllanalysis:CLLPatientTherapyPeriod11InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod11]]]]].

cllanalysis:CLLPatientTherapyPeriod12InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod12]]]]].

cllanalysis:CLLPatientTherapyPeriod13InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod13]]]]].

cllanalysis:CLLPatientTherapyPeriod14InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod14]]]]].

cllanalysis:CLLPatientTherapyPeriod15InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod15]]]]].

cllanalysis:CLLPatientUpToTherapyPeriod1InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod1]]]]].

cllanalysis:CLLPatientUpToTherapyPeriod2InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod2]]]]].

cllanalysis:CLLPatientUpToTherapyPeriod3InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod3]]]]].

cllanalysis:CLLPatientUpToTherapyPeriod4InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod4]]]]].

cllanalysis:CLLPatientUpToTherapyPeriod5InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod5]]]]].

cllanalysis:CLLPatientUpToTherapyPeriod6InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod6]]]]].

cllanalysis:CLLPatientUpToTherapyPeriod7InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod7]]]]].

cllanalysis:CLLPatientUpToTherapyPeriod8InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod8]]]]].

cllanalysis:CLLPatientUpToTherapyPeriod9InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod9]]]]].

cllanalysis:CLLPatientUpToTherapyPeriod10InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod10]]]]].

cllanalysis:CLLPatientUpToTherapyPeriod11InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod11]]]]].

cllanalysis:CLLPatientUpToTherapyPeriod12InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod12]]]]].

cllanalysis:CLLPatientUpToTherapyPeriod13InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod13]]]]].

cllanalysis:CLLPatientUpToTherapyPeriod14InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod14]]]]].

cllanalysis:CLLPatientUpToTherapyPeriod15InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf human:Person, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient], [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty time:beginsBeforeEndOf; owl:hasValue [
					time:begins [a xsd:dateTime];
					time:ends [a xsd:dateTime]], [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					a owl:Restriction; owl:onProperty cllwf:hasWorkflowPeriod; owl:hasValue cllwf:TherapyPeriod15]]]]].

cllanalysis:CLLPatientWithBRTherapyPeriod1InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod1InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom chemo:BR]]].

cllanalysis:CLLPatientWithBRTherapyPeriod2InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod2InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom chemo:BR]]].

cllanalysis:CLLPatientWithBRTherapyPeriod3InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod3InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom chemo:BR]]].

cllanalysis:CLLPatientWithBRTherapyPeriod4InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod4InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom chemo:BR]]].

cllanalysis:CLLPatientWithBRTherapyPeriod5InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod5InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom chemo:BR]]].

cllanalysis:CLLPatientWithBRTherapyPeriod6InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod6InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom chemo:BR]]].

cllanalysis:CLLPatientWithBRTherapyPeriod7InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod7InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom chemo:BR]]].

cllanalysis:CLLPatientWithBRTherapyPeriod8InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod8InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom chemo:BR]]].

cllanalysis:CLLPatientWithBRTherapyPeriod9InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod9InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom chemo:BR]]].

cllanalysis:CLLPatientWithBRTherapyPeriod10InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod10InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom chemo:BR]]].

cllanalysis:CLLPatientWithBRTherapyPeriod11InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod11InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom chemo:BR]]].

cllanalysis:CLLPatientWithBRTherapyPeriod12InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod12InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom chemo:BR]]].

cllanalysis:CLLPatientWithBRTherapyPeriod13InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod13InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom chemo:BR]]].

cllanalysis:CLLPatientWithBRTherapyPeriod14InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod14InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom chemo:BR]]].

cllanalysis:CLLPatientWithBRTherapyPeriod15InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod15InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom chemo:BR]]].

cllanalysis:CLLPatientWithFCRTherapyPeriod1InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod1InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom chemo:FCR]]].

cllanalysis:CLLPatientWithChlorambucilTherapyPeriod1InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod1InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Chlorambucil]]]]].

cllanalysis:CLLPatientWithBendamustinTherapyPeriod2InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod2InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientWithBendamustinTherapyPeriod3InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod3InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientWithBendamustinTherapyPeriod4InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod4InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientWithBendamustinTherapyPeriod5InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod5InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientWithBendamustinTherapyPeriod6InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod6InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientWithBendamustinTherapyPeriod7InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod7InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientWithBendamustinTherapyPeriod8InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod8InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientWithBendamustinTherapyPeriod9InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod9InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientWithBendamustinTherapyPeriod10InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod10InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientWithBendamustinTherapyPeriod11InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod11InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientWithBendamustinTherapyPeriod12InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod12InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientWithBendamustinTherapyPeriod13InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod13InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientWithBendamustinTherapyPeriod14InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod14InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientWithBendamustinTherapyPeriod15InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod15InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientWithBendamustinTherapyPeriod2InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod2InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientWithBendamustinTherapyPeriod3InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod3InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientWithBendamustinTherapyPeriod4InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod4InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientWithBendamustinTherapyPeriod5InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod5InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientWithBendamustinTherapyPeriod6InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod6InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientWithBendamustinTherapyPeriod7InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod7InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientWithBendamustinTherapyPeriod8InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod8InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientWithBendamustinTherapyPeriod9InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod9InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientWithBendamustinTherapyPeriod10InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod10InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientWithBendamustinTherapyPeriod11InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod11InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientWithBendamustinTherapyPeriod12InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod12InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientWithBendamustinTherapyPeriod13InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod13InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientWithBendamustinTherapyPeriod14InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod14InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].

cllanalysis:CLLPatientWithBendamustinTherapyPeriod15InCertainPeriod
	a rdfs:class;
	rdfs:subClassOf cllanalysis:CLLPatientTherapyPeriod15InCertainPeriod, [
		a owl:Restriction; owl:onProperty humdis:hasDisorder; owl:someValuesFrom [
			rdfs:subClassOf cll:BCellChronicLymphocyticLeukemia, [
				a owl:Restriction; owl:onProperty ther:treatedWith; owl:someValuesFrom [
					rdfs:subClassOf drug:Monotherapy, [
						a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin]]]]].