@prefix dce: <http://purl.org/dc/elements/1.1/>.
@prefix owl: <http://www.w3.org/2002/07/owl#>.
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#>.
@prefix skos: <http://www.w3.org/2004/02/skos/core#>.
@prefix agent: <http://eulersharp.sourceforge.net/2003/03swap/agent#>.
@prefix clisko: <http://www.agfa.com/w3c/2009/clinicalSKOSSchemes#>.
@prefix drug: <http://www.agfa.com/w3c/2009/drugTherapy#>.
@prefix glucor: <http://www.agfa.com/w3c/2009/glucocorticoids#>.
@prefix antineo: <http://www.agfa.com/w3c/2009/antineoplastics#>.
@prefix chemo: <http://www.agfa.com/w3c/2009/chemotherapy#>.

<http://www.agfa.com/w3c/2009/chemotherapy>
	a owl:Ontology;
	dce:title """Chemotherapy"""@en;
	dce:creator """Hans Cools, MD, Agfa Healthcare/Belgium"""@en;
	dce:publisher """Agfa Healthcare/Belgium"""@en;
	dce:description """Formal general description of chemotherapy as applied in human medicine."""@en;
	dce:format """OWL Full"""@en;
	rdfs:comment """Copyright (c) 2009 Agfa-Gevaert Group / All Rights Reserved. THIS IS UNPUBLISHED PROPRIETARY SOURCE CODE OF Agfa-Gevaert Group/ The copyright notice above does not evidence any actual or intended publication of such source code."""@en.

#
# CLASSES
#

chemo:Therapy
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """chemotherapy"""@en;
	skos:definition """Clinical therapy implying administration of an antineoplastic drug."""@en;
	rdfs:subClassOf drug:Therapy, [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom [
			a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom chemo:Antineoplastic]];
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "367336001"^^clisko:sct20080731DT].

chemo:Monotherapy
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """monochemotherapy"""@en;
	skos:definition """Chemotherapy implying administration of 1 antineoplastic drug."""@en;
	rdfs:subClassOf chemo:Therapy, drug:Monotherapy.

chemo:Polytherapy
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """polychemotherapy"""@en;
	skos:definition """Chemotherapy implying administration of 2 or more antineoplastic drugs."""@en;
	rdfs:subClassOf chemo:Therapy, drug:Polytherapy.

chemo:Antineoplastic
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """antineoplastic"""@en;
	skos:definition """Role of a substance killing or inhibiting the growth of a neoplastic human cell."""@en;
	rdfs:subClassOf drug:Role;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "27867009"^^clisko:sct20080731DT], [
		a skos:Concept; skos:inScheme clisko:atc20090101; skos:notation "L01"^^clisko:atc20090101DT].

chemo:Alkylator
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """alkylating clinical drug substance"""@en;
	skos:definition """Antineoplastic ."""@en;
	rdfs:subClassOf drug:Substance, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom chemo:Antineoplastic];
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:atc20090101; skos:notation "L01A"^^clisko:atc20090101DT].

chemo:NitrogenMustardAnalogue
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """nitrogen mustard analogue"""@en;
	skos:definition """Alkylating drug ."""@en;
	rdfs:subClassOf chemo:Alkylator;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:atc20090101; skos:notation "L01AA"^^clisko:atc20090101DT].

chemo:Nitrosourea
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """nitrosourea"""@en;
	skos:definition """Alkylating drug ."""@en;
	rdfs:subClassOf chemo:Alkylator;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:atc20090101; skos:notation "L01AD"^^clisko:atc20090101DT].

chemo:Antimetabolite
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """antimetabolitic clinical drug substance"""@en;
	skos:definition """Inhibitor of a metabolite, playing an antineoplastic role."""@en;
	rdfs:subClassOf drug:Substance, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom chemo:Antineoplastic];
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:atc20090101; skos:notation "L01B"^^clisko:atc20090101DT].

chemo:FolicAcidAnalogue
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """folic acid analogue"""@en;
	skos:definition """Antimetabolite ."""@en;
	rdfs:subClassOf chemo:Antimetabolite;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:atc20090101; skos:notation "L01BA"^^clisko:atc20090101DT].

chemo:PurineAnalogue
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """purine analogue"""@en;
	skos:definition """Antimetabolite ."""@en;
	rdfs:subClassOf chemo:Antimetabolite;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:atc20090101; skos:notation "L01BB"^^clisko:atc20090101DT].

chemo:PyrimidineAnalogue
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """pyrimidine analogue"""@en;
	skos:definition """Antimetabolite ."""@en;
	rdfs:subClassOf chemo:Antimetabolite;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:atc20090101; skos:notation "L01BC"^^clisko:atc20090101DT].

chemo:Alkaloid
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """alkaloid clinical drug substance"""@en;
	skos:definition """Antineoplastic ."""@en;
	rdfs:subClassOf drug:Substance, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom chemo:Antineoplastic];
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:atc20090101; skos:notation "L01C"^^clisko:atc20090101DT].

chemo:VincaAlkaloid
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """alkaloid"""@en;
	skos:definition """Alkaloid from Catharanthus roseus and also produced synthetically."""@en;
	rdfs:subClassOf chemo:Alkaloid;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:atc20090101; skos:notation "L01CA"^^clisko:atc20090101DT].

chemo:PodophyllotoxinDerivative
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """podophyllotoxin derivative"""@en;
	skos:definition """Alkaloid ."""@en;
	rdfs:subClassOf chemo:Alkaloid;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:atc20090101; skos:notation "L01CB"^^clisko:atc20090101DT].

chemo:CytotoxicAntibiotic
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """cytotoxic antibiotic clinical drug substance"""@en;
	skos:definition """Antineoplastic ."""@en;
	rdfs:subClassOf drug:Substance, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom chemo:Antineoplastic];
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:atc20090101; skos:notation "L01D"^^clisko:atc20090101DT].

chemo:Anthracycline
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """anthracycline"""@en;
	skos:definition """Cytotoxic antibiotic ."""@en;
	rdfs:subClassOf chemo:CytotoxicAntibiotic;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:atc20090101; skos:notation "L01DB"^^clisko:atc20090101DT].

chemo:Anthracenedione
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """anthracenedione"""@en;
	skos:definition """Cytotoxic antibiotic ."""@en;
	rdfs:subClassOf chemo:CytotoxicAntibiotic.

chemo:MonoclonalAntibody
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """monoclonal antibody"""@en;
	skos:definition """Antibody binding to cell-specific antigen and inducing an immunological response against target cell."""@en;
	rdfs:subClassOf drug:Substance, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom chemo:Antineoplastic];
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:atc20090101; skos:notation "L01XC"^^clisko:atc20090101DT].

chemo:MonoclonalAntibodyTherapy
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """monoclonal antibody therapy"""@en;
	skos:definition """Cancer therapy wherein monoclonal antibodies are administered, binding to cancer cell-specific antigens and inducing an immunological response against target cancer cell."""@en;
	rdfs:subClassOf drug:Therapy, [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom chemo:MonoclonalAntibody].

chemo:ProteinKinaseInhibitor
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """protein kinase inhibitor"""@en;
	skos:definition """."""@en;
	rdfs:subClassOf drug:Substance, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom chemo:Antineoplastic];
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:atc20090101; skos:notation "L01XE"^^clisko:atc20090101DT].

chemo:PlatinumCompound
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """platinum compound"""@en;
	skos:definition """."""@en;
	rdfs:subClassOf drug:Substance, [
		a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom chemo:Antineoplastic];
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:atc20090101; skos:notation "L01XA"^^clisko:atc20090101DT].

chemo:BEAM
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """BEAM polychemotherapy"""@en;
	skos:definition """Polychemotherapy implying administration of BCNU (carmustine), etoposid, cytosin-arabinosid (cytarabine), and melphalan."""@en;
	rdfs:subClassOf chemo:Polytherapy, [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Carmustine], [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Etoposide], [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Cytarabine], [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Melphalan].

chemo:BM
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """BM polychemotherapy"""@en;
	skos:definition """Polychemotherapy implying administration of bendamustin, mitoxantron."""@en;
	rdfs:subClassOf chemo:Polytherapy.

chemo:BMR
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """BMR polychemotherapy"""@en;
	skos:definition """Polychemotherapy implying administration of bendamustin, mitoxantron, rituximab."""@en;
	rdfs:subClassOf chemo:Polytherapy.

chemo:BOP
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """BOP polychemotherapy"""@en;
	skos:definition """Polychemotherapy implying administration of bendamustin, adriamycin (doxorubicin), prednisone."""@en;
	rdfs:subClassOf chemo:Polytherapy.

chemo:BP
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """BP polychemotherapy"""@en;
	skos:definition """Polychemotherapy implying administration of bendamustin, prednisone."""@en;
	rdfs:subClassOf chemo:Polytherapy, [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin], [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom glucor:Prednisone].

chemo:BR
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """BR polychemotherapy"""@en;
	skos:definition """Polychemotherapy implying administration of bendamustin, rituximab."""@en;
	rdfs:subClassOf chemo:Polytherapy;
	owl:equivalentClass [owl:intersectionOf ([
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Bendamustin] [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Rituximab])].

chemo:CAP
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """CAP polychemotherapy"""@en;
	skos:definition """Polychemotherapy implying administration of cyclophosphamide, adriamycin (doxorubicin), prednisone."""@en;
	rdfs:subClassOf chemo:Polytherapy.

chemo:CHOP
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """CHOP polychemotherapy"""@en;
	skos:definition """Polychemotherapy implying administration of cyclophosphamide, adriamycin (doxorubicin), vincristine, prednisone."""@en;
	rdfs:subClassOf chemo:Polytherapy.

chemo:CHOPR
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """CHOPR polychemotherapy"""@en;
	skos:definition """Polychemotherapy implying administration of cyclophosphamide, adriamycin (doxorubicin), vincristine, prednisone, rituximab."""@en;
	rdfs:subClassOf chemo:Polytherapy.

chemo:CLBR
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """CLB-R polychemotherapy"""@en;
	skos:definition """Polychemotherapy implying administration of chlorambucil, rituximab."""@en;
	rdfs:subClassOf chemo:Polytherapy, [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Chlorambucil], [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Rituximab].

chemo:CLBGA101
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """CLB-GA101 polychemotherapy"""@en;
	skos:definition """Polychemotherapy implying administration of chlorambucil, obinutuzumab."""@en;
	rdfs:subClassOf chemo:Polytherapy.

chemo:COP
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """COP polychemotherapy"""@en;
	skos:definition """Polychemotherapy implying administration of cyclophosphamide, vincristine, prednisone."""@en;
	rdfs:subClassOf chemo:Polytherapy.

chemo:DEXABEAM
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """DEXABEAM polychemotherapy"""@en;
	skos:definition """Polychemotherapy implying administration of dexamethasone, BCNU (carmustine), etoposide, cytosin-arabinosid (cytarabine), melphalan."""@en;
	rdfs:subClassOf chemo:Polytherapy, [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom glucor:Dexamethasone], [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Carmustine], [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Etoposide], [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Cytarabine], [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Melphalan].

chemo:DHAP
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """DHAP polychemotherapy"""@en;
	skos:definition """Polychemotherapy implying administration of dexamethasone, cytosin-arabinosid (cytarabine), cisplatin."""@en;
	rdfs:subClassOf chemo:Polytherapy.

chemo:DHAPR
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """DHAP-R polychemotherapy"""@en;
	skos:definition """Polychemotherapy implying administration of dexamethasone, cytosin-arabinosid (cytarabine), cisplatin, rituximab."""@en;
	rdfs:subClassOf chemo:Polytherapy.

chemo:FDARBO
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """F+DARBO polychemotherapy"""@en;
	skos:definition """Polychemotherapy implying administration of fludarabine, darbepoetin alfa."""@en;
	rdfs:subClassOf chemo:Polytherapy.

chemo:FC
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """FC polychemotherapy"""@en;
	skos:definition """Polychemotherapy implying administration of fludarabine, cyclophosphamide."""@en;
	rdfs:subClassOf chemo:Polytherapy.

chemo:FCA
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """FCA polychemotherapy"""@en;
	skos:definition """Polychemotherapy implying administration of fludarabine, cyclophosphamide, alemtuzumab."""@en;
	rdfs:subClassOf chemo:Polytherapy.

chemo:FCM
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """FCM polychemotherapy"""@en;
	skos:definition """Polychemotherapy implying administration of fludarabine, cyclophosphamide, mitoxantrone."""@en;
	rdfs:subClassOf chemo:Polytherapy.

chemo:FCR
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """FCR polychemotherapy"""@en;
	skos:definition """Polychemotherapy implying administration of fludarabine, cyclophosphamide, rituximab."""@en;
	rdfs:subClassOf chemo:Polytherapy.

chemo:FM
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """FM polychemotherapy"""@en;
	skos:definition """Polychemotherapy implying administration of fludarabine, mitoxantrone."""@en;
	rdfs:subClassOf chemo:Polytherapy, [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Fludarabine], [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Mitoxantrone].

chemo:Knospe
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """Knospe polychemotherapy"""@en;
	skos:definition """Polychemotherapy implying administration of chlorambucil, prednisone."""@en;
	rdfs:subClassOf chemo:Polytherapy, [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Chlorambucil], [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom glucor:Prednisone].

chemo:MCP
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """MCP polychemotherapy"""@en;
	skos:definition """Polychemotherapy implying administration of mitoxantron, chlorambucil, prednisone."""@en;
	rdfs:subClassOf chemo:Polytherapy, [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Mitoxantrone], [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Chlorambucil], [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom glucor:Prednisone].


chemo:MCPR
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """MCPR polychemotherapy"""@en;
	skos:definition """Polychemotherapy implying administration of mitoxantron, chlorambucil, prednisone, rituximab."""@en;
	rdfs:subClassOf chemo:Polytherapy, [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Mitoxantrone], [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Chlorambucil], [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom glucor:Prednisone], [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Rituximab].

chemo:MiniCHOP
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """Mini-CHOP polychemotherapy"""@en;
	skos:definition """Polychemotherapy implying administration of cyclophosphamide, adriamycin (doxorubicin), vincristine, prednisone."""@en;
	rdfs:subClassOf chemo:Polytherapy, [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Cyclophosphamide], [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Doxorubicin], [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Vincristine], [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom glucor:Prednisone].

chemo:PC
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """PC polychemotherapy"""@en;
	skos:definition """Polychemotherapy implying administration of deoxycoformycin (pentostatin), cyclophosphamide."""@en;
	rdfs:subClassOf chemo:Polytherapy, [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Pentostatin], [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Cyclophosphamide].

chemo:PCR
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/chemotherapy#>;
	rdfs:label """PCR polychemotherapy"""@en;
	skos:definition """Polychemotherapy implying administration of deoxycoformycin (pentostatin), cyclophosphamide, rituximab."""@en;
	rdfs:subClassOf chemo:Polytherapy, [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Pentostatin], [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Cyclophosphamide], [
		a owl:Restriction; owl:onProperty drug:whereinAdministered; owl:someValuesFrom antineo:Rituximab].